Metals and their alloys are one of the oldest biomedical materials known to human beings. They still play an irreplaceable role in modern clinical treatment with excellent mechanical load-bearing properties, chemical stability, and good biocompatibility. In recent years, the R&D and design of metal implants and devices, the further exploration of their powerful functions, and the in-depth exploration of their interaction with the body microenvironment have made great progress. In particular, the design of biodegradable alloys, the elaboration of their degradation mechanism in different environments, the research on degradation behavior and degradation products, and the prospect of their advanced exclusive coating have attracted the attention of scholars. The aim of this reprint, “Advanced Alloy Degradation and Implants”, is to publish full-length research articles, short communications, and review articles covering the latest studies, progress, and challenges on the design, fabrication, degradation, and surface modification of metal alloy implants for their future biomedical applications.

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We are very pleased to introduce the Book Version of our Special Issue in Molecules dedicated to the memory of the late Professor Dr. Charles D. Hufford. The issue has been a huge success, with 22 full-length peer-reviewed papers and a tribute by Professor Alice M.Clark. Authors, reviewers, and collaborators from many countries across the worldhave contributed to this endeavour, and we are truly grateful to all. This Special Issue isrepresentative of the broad impact that “Charlie” had on the field of bioactive naturalproducts. This Special Issue comprises papers from Professor Hufford’s former students,colleagues, and collaborators throughout the world who have utilized a wide array ofstate-of-the-art techniques to examine diverse natural sources to isolate and identify avariety of natural products with a wide spectrum of biological activities, including somenew microbial transformations and insights into bioactive molecules. Many new bioactive compounds are described and reported here for the first time. Bioactivities reportedinclude cytotoxicity, antimicrobial activity, anti-inflammatory activity, antileishmanialactivity, antitrypanosomal activity, antimalarial activity, analgesic activity, and beneficialliver activities, just to name a few. This Special Issue will undoubtedly have a lasting impact on the field of bioactive natural products, as exemplified by the career of Dr. Hufford.Lastly, without the timely and outstanding contributions from all of you, this Special Issue would not have been possible. We thank you all very much for your contributions and your time devoted to this Special Issue in memory of a special person. Finally, we express ourgratitude and thanks to the journal Molecules and their excellent team of expert reviewers for giving us the support and opportunity to make this Special Issue a huge success!

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This book outlines some new advances in genetics, clinical evaluation, localization, therapy (newly including immunotherapy) of pheochromocytoma and paraganglioma including their metastatic counterparts. Well-known and experienced clinicians and scientists contributed to this book to include some novel approaches to these tumors. This book will serve to various health care professionals from different subspecialties, but mainly oncologists, endocrinologists, endocrine surgeons, pediatricians, and radiologists. This book shows that the field of pheochromocytoma/paraganglioma is evolving and a significant progress has been made in last 5 years requiring that health care professionals and scientists will learns new information and implement it in their clinical practice or scientific work, respectively. This book should not be missed by anybody who is focusing on neuroendocrine tumors, their newest evaluation and treatment.

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This Special Issue, "Scientific Papers by Developmental Biologists in Japan", represents a collection of high-quality review articles, research articles, and communications on the development of multicellular organisms at the molecule, cell, tissue, organ, and whole-organism level, which were written and submitted by developmental biologists working in Japan.

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