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Drug-Acceptor Interactions: Modeling theoretical tools to test and evaluate experimental equilibrium effects suggests novel theoretical tools to test and evaluate drug interactions seen with combinatorial drug therapy. The book provides an in-depth, yet controversial, exploration of existing tools for analysis of dose-response studies at equilibrium or steady state. The book is recommended reading for post-graduate students and researchers engaged in the study of systems biology, networks, and the pharmacodynamics of natural or industrial drugs, as well as for medical clinicians interested in drug application and combinatorial drug therapy. Even people without mathematical skills will be able to follow the pros and cons of reaction schemes and their related distribution equations. Chapter 9 is a hands-on guide for software to plot, fit and analyze one’s own data.
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Keywords
- Analysis
- Ant Agonist Concentration
- binding
- binding sites
- Competitive Ant Agonism
- ENaC
- Equilibrium Dissociation Constants
- FRA
- Fra Ct
- Inverse Agonists
- Lr Es
- MWC Model
- Negative Co-operativity
- Primary Ligand
- reaction
- Reaction Scheme
- receptive
- Receptive Units
- receptor
- Receptor Conformations
- RR
- scheme
- schild
- Schild Analysis
- Schild’s Plot
- Secondary Binding Site
- Semi-log Plots
- sites
- Ternary Complex Model
- thema EDItEUR::M Medicine and Nursing::MQ Nursing and ancillary services
- thema EDItEUR::M Medicine and Nursing::MR Medical study and revision guides and reference material
- unit
Links
DOI: 10.4324/9781315159782Editions