Explore
Neurobiological circuit function and computation of the serotonergic and related systems
KongFatt Wong-Lin and Kae Nakamura
2015
0 Ungluers have
Faved this Work
Login to Fave
Serotonin is one of the oldest neurotransmitters in evolutionary terms, and the serotonergic system is complex and multifaceted. Serotonin-producing neurons in the raphe nuclei provide serotonin innervations throughout various parts of the brain, modulating cellular excitability and network properties of targeted brain areas, and regulating mood, cognition and behavior. Dysfunctions of the serotonergic system are implicated in neuropsychiatric disorders including depression, schizophrenia, and drug abuse. Although the system has been studied for many years, an integrative account of its functions and computational principles remains elusive. This is partly attributed to the high variability and heterogeneity in terms of neuronal properties and receptor types, and its extensive connections with other brain regions. This Frontiers Research Topic e-book is a collection of recent experimental and computational work and approaches at multiple scales that provide the latest information regarding the integrated functions of the serotonergic system. The contributed papers include a variety of experimental and computational work, and human clinical studies.
This book is included in DOAB.
Why read this book? Have your say.
You must be logged in to comment.
Rights Information
Are you the author or publisher of this work? If so, you can claim it as yours by registering as an Unglue.it rights holder.Downloads
This work has been downloaded 110 times via unglue.it ebook links.
- 46 - mobi (CC BY) at Unglue.it.
- 35 - epub (CC BY) at Unglue.it.
- 29 - pdf (CC BY) at Unglue.it.
Keywords
- computational modeling
- Dopamine
- dorsal raphe nucleus
- Locus Coeruleus
- neural circuit
- pendunculopontine tegmental nucleus
- Serotonin
- serotonin 5-HT