Explore
Pathophysiological Mechanisms of Sarcopenia in Aging and in Muscular Dystrophy: A Translational Approach
0 Ungluers have
Faved this Work
Login to Fave
Loss of muscle mass and increased fibrosis characterize both sarcopenia of aging and muscular dystrophy. Research is increasingly showing that these two conditions also share several pathophysiological mechanisms, including mitochondrial dysfunction, increased apoptosis, abnormal modulation of autophagy, decline in satellite cells, increased generation of reactive oxygen species, and abnormal regulation of signaling and stress response pathways. This Research Topic will cover several mechanisms involved in aging and dystrophic sarcopenia and explore the therapeutic potential of various strategies for intervention.
This book is included in DOAB.
Why read this book? Have your say.
You must be logged in to comment.
Rights Information
Are you the author or publisher of this work? If so, you can claim it as yours by registering as an Unglue.it rights holder.Downloads
This work has been downloaded 113 times via unglue.it ebook links.
- 49 - mobi (CC BY) at Unglue.it.
- 27 - epub (CC BY) at Unglue.it.
- 37 - pdf (CC BY) at Unglue.it.
Keywords
- Aging sarcopenia
- Animal Models
- Apoptosis
- Autophagy
- Mitochondrial dysfunction
- muscle imaging
- muscular dystrophy
- satellite cells
- skeletal muscle
- Therapy
Links
DOI: 10.3389/978-2-88919-684-5Editions