Explore
Toxins in Drug Discovery and Pharmacology
0 Ungluers have
Faved this Work
Login to Fave
Venoms from marine and terrestrial animals (cone snails, scorpions, spiders, snakes, centipedes, cnidarian, etc.) can be seen as untapped cocktails of biologically active compounds that are being increasingly recognized as a new emerging source of peptide-based therapeutics. Venomous animals are considered to be specialized predators that have evolved the most sophisticated peptide chemistry and neuropharmacology for their own biological purposes by producing venoms that contain a structural and functional diversity of neurotoxins. These neurotoxins appear to be highly selective ligands for a wide range of ion channels and receptors. Therefore, they represent interesting lead compounds for the development of analgesics, anti-cancer drugs, drugs for neurological disorders such as multiple sclerosis, Parkinson' s disease, Alzheimer' s disease, and other therapeutics.This Special Issue of Toxins aims to provide a comprehensive look at toxins and toxin-inspired leads and will focus on the mechanisms of action, structure–function relationships, and evolution of pharmacologically interesting venom components, including the most recent developments related to the emergence of venoms as an underutilized source of highly evolved bioactive peptides with clinical potential.
This book is included in DOAB.
Why read this book? Have your say.
You must be logged in to comment.
Rights Information
Are you the author or publisher of this work? If so, you can claim it as yours by registering as an Unglue.it rights holder.Downloads
This work has been downloaded 313 times via unglue.it ebook links.
- 4 - pdf (CC BY-NC-ND) at Unglue.it.
Keywords
- acetylcholine receptors
- antibiotics
- antimicrobial peptides
- ASIC channels
- botulinum toxins
- calcium channels
- chloride ion channels
- cone snail venom
- medicine
- NMDA receptor
- opiate receptors
- Other branches of medicine
- Peptides
- Pharmacology
- potassium channels
- sodium channels
- spider venom peptides
- thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology
- TRP channels
Editions
