Explore
On the Origin and Function of Human NK-like CD8+ T Cells: Charting New Territories
Fernando A. Arosa
2018
0 Ungluers have
Faved this Work
Login to Fave
Human CD8+ T cells expressing NK receptors and receptors found on innate immune cells, and designated as NK-like or innate CD8+ T cells, have been long considered as terminally differentiated lymphocytes responsible for tissue inflammation and destruction. However, a growing body of knowledge is unveiling that NK-like CD8+ T cells have many, sometimes contrasting, functions. The limited knowledge of the biology of this type of CD8+ T cells and the role they play within peripheral tissues and organs under homeostatic conditions has hampered our understanding of disease and therefore the possible development of disease diagnostic tools and effective immunotherapies. In this Research Topic are presented a variety of topics and views, some of them overlooked for many years, on human NK-like CD8+ T cells, which may open new and novel avenues of research to further our understanding of these polyfunctional T cells.
This book is included in DOAB.
Why read this book? Have your say.
You must be logged in to comment.
Rights Information
Are you the author or publisher of this work? If so, you can claim it as yours by registering as an Unglue.it rights holder.Downloads
This work has been downloaded 97 times via unglue.it ebook links.
- 37 - mobi (CC BY) at Unglue.it.
- 33 - epub (CC BY) at Unglue.it.
- 27 - pdf (CC BY) at Unglue.it.
Keywords
- Adaptive
- Cytotoxic
- Disease control
- Innate receptors
- MHC class I
- Open conformers
- Regulatory
- Successful aging
- Suppressor
- Tissue repair
Links
DOI: 10.3389/978-2-88945-396-2Editions