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Extraintestinal Manifestations of Coeliac Disease
Marios Hadjivassiliou and David Sanders
2019
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Coeliac Disease (CD) affects at least 1% of the population. “Classical” CD refers to gastrointestinal presentations with anaemia and gastrointestinal symptoms. CD can, however, present with extraintestinal manifestations, the commonest of which are dermatitis herpetiformis and neurological presentations (e.g., ataxia, neuropathy, encephalopathy). Recognition and research into the pathophysiology of such manifestations is likely to enhance our understanding of this complex autoimmune disorder.
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Keywords
- ADHD
- alopecia areata
- antigliadin antibodies
- antigliadin antibody titre
- anxiety disorders
- atopic dermatitis
- Autism
- autoantibody
- autoimmune pancreatitis
- autoimmune thyroid disease
- Autoimmunity
- B cell
- biomarker
- bone health
- celiac disease
- celiac hepatitis
- celiac trait
- Children and adults
- clinical presentation
- coeliac disease
- cutaneous vasculitis
- Depression
- dermatitis herpetiformis
- Diagnosis
- early developing celiac disease
- Eating Disorders
- energy
- epidermal transglutaminase
- extra-intestinal
- extra-intestinal manifestations
- extraintestinal
- Fatigue
- Fracture
- Fractures
- ganglioside
- gastrointestinal
- gastrointestinal symptoms
- genetic gluten intolerance
- Gilles de la Tourette syndrome (GTS)
- glandular autoimmunity
- gliadin
- gluten
- Gluten ataxia
- gluten free diet
- gluten neuropathy
- gluten sensitive enteropathy
- gluten sensitivity
- Gluten-free diet
- gut–liver axis
- headache
- incidence
- intermolecular help
- intestinal barrier
- latent celiac disease
- liver immunity
- long-term prognosis
- Male
- migraine
- mild enteropathy
- molecular mimicry
- motor and vocal/phonic tics
- Movement Disorders
- MR spectroscopy
- Natural history
- non-alcoholic fatty liver disease
- non-celiac gluten sensitivity
- non-coeliac gluten sensitivity (NCGS)
- obsessive-compulsive disorder (OCD)
- one-year adherence
- osteoporosis
- pancreatic disorders
- polyglandular autoimmune syndrome
- potential celiac disease
- Prevalence
- prognosis
- psoriasis
- psychiatric disorders
- psychosis
- Quality of life
- recognition
- recurrent aphtous ulceration
- rosacea
- screening
- small bowel
- synapsin
- T cell
- tolerance
- Transglutaminase
- Type 1 Diabetes
- urticaria
- villous atrophy