Explore
Peroxiredoxin 6 as a Unique Member of the Peroxiredoxin Family
Aron B. Fisher
2019
0 Ungluers have
Faved this Work
Login to Fave
The peroxiredoxin family was discovered approximately 30 years ago and is now recognized as one of the most important families of enzymes related to antioxidant defense and cellular signaling. Peroxiredoxin 6 shares the basic enzymatic functions that characterize this family, but also exhibits several unique and crucial activities. These include the ability to reduce phospholipid hydroperoxides, phospholipase A2 activity, and an acyl transferase activity that is important in phospholipid remodeling. This book describes the available models for investigating the unique functions of PRDX6 and its role in normal physiological function, as well its roles in the pathophysiology of diseases including cancer, diseases of the eye, and male fertility.
This book is included in DOAB.
Why read this book? Have your say.
You must be logged in to comment.
Rights Information
Are you the author or publisher of this work? If so, you can claim it as yours by registering as an Unglue.it rights holder.Downloads
This work has been downloaded 231 times via unglue.it ebook links.
- 17 - pdf (CC BY-NC-ND) at Unglue.it.
Keywords
- 1-Cys Prdx
- antioxidant activity
- cornea
- diabetes
- Drug delivery
- Endothelium
- fertilization
- Fuchs’ endothelial corneal dystrophy
- glutathione peroxidase
- Inflammation
- Ionizing radiation
- knock-in mouse
- knockout mouse
- Lipid Peroxidation
- liposomes
- mass spectroscopic analysis
- medicine
- membrane repair
- mitochondrial membrane potential
- n/a
- NADPH (nicotinamide adenine dinucleotide phosphate) oxidase
- Oxidative Stress
- peroxidase
- peroxidatic cysteine
- Peroxiredoxin
- peroxiredoxin 6
- phospholipase A2
- phospholipase A2 activity
- phospholipid hydroperoxide
- PLA2 activity
- Prdx6
- Prdx6 structure
- radioprotection
- Reactive Oxygen Species
- redox balance
- sperm capacitation
- spermatozoa
- substrate binding
- sulfinic acid
- sulfonic/sulfinic acid
- surfactant protein A
- thioredoxin fold
Links
DOI: 10.3390/books978-3-03897-935-7Editions
