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Bioactive Compounds from Marine-Derived Aspergillus, Penicillium, Talaromyces and Trichoderma Species
Rosario Nicoletti and Francesco Vinale
2019
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The importance of bioactive natural compounds in pharmacology and other biotechnological fields has stimulated the scientific community to explore new environmental contexts and their associated microbial diversity. As the largest frontier in biological discovery, the sea represents a significant source of organisms producing novel secondary metabolites with interesting bioactivities. Of the available biological material, fungi have received increasing consideration, both due to their pervasive occurrence in varying habitats as well as their aptitude to develop symbiotic associations with higher organisms in numerous contexts. In many cases, fungal strains have been reported as the real producers of drugs originally extracted from marine plants and animals. Due to the constantly increasing number of marine-derived fungi yielding valuable bioactive products, it is now appropriate to present these findings to a recipient audience in a more organized form. This Special Issue of Marine Drugs, entitled “Bioactive Compounds from Marine-Derived Aspergillus, Penicillium, Talaromyces, and Trichoderma Species"" is specifically focused on a few genera of ascomycetous fungi which are widespread regarding marine contexts and are particularly inclined to establishing symbiotic relationships. For this project, we welcome submissions of full research papers, short notes, and review articles reporting the discovery and characterization of products showing antibiotic, antitumor, antiviral, insecticidal, antimalarial, antifouling, antioxidant, plant growth-promoting and/or resistance-inducing, as well as other less-exploited activities.
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Keywords
- antibacterial
- Antibacterial activity
- antifungal activity
- Aspergillaceae
- Aspergillus
- Aspergillus candidus
- Aspergillus clavatus
- aspetritone
- bioactive products
- bis-indolyl benzenoids
- BK (Maxi-K) channel
- Breast cancer
- breviane spiroditerpenoid
- candidusin
- chromone
- coumarin
- Cytotoxic
- cytotoxicities
- Cytotoxicity
- diastereomers
- diterpenoid
- Drug Discovery
- ECD calculations
- EGFR
- endophytic fungi
- gefitinib
- HER2
- hydroxypyrrolidine
- IDH1 inhibitory activity
- indole-diterpenoids
- lapatinib
- mangrove endophytic fungus
- mangroves
- marine-derived fungi
- n/a
- NMR data calculations
- Penicillium raistrickii
- Penicillium sp. TJ403-1
- penitrem A
- polyketides
- secondary metabolites
- sesquiterpenoid
- sponge-associated fungus
- sterone
- Talaromyces
- Talaromyces purpurogenus
- thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
- thermo-change strategy
- TNF-?
Links
DOI: 10.3390/books978-3-03897-981-4Editions
