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Staphylococcus aureus is a common inhabitant of the human body with which we co-exist. However, this species can also cause disease in humans when an appropriate opportunity arises, such as a cut or some other breakdown in our body’s defenses. S. aureus is able to initiate infections due, in part, to the diverse group of toxins that they secrete. The exotoxins produced by S. aureus can cause direct damage, thwart our own body’s defenses, or trigger massive amounts of cytokines that lead to indirect damage within the human body. In this book are 12 research articles that deal with different aspects of staphylococcal exotoxins. Some of the work gives an overview about how the toxins contribute to the disease process. Other articles discuss different aspects of several exotoxins, and two articles are centered on countermeasures against S. aureus infections. Overall, this book will give the reader a good overview of how staphylococcal exotoxins contribute to initiating and sustaining infections in humans.
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Keywords
- Adaptive Immunity
- airway epithelial cells
- alpha-toxin
- atopic dermatitis
- butyric acid derivative
- canned meat
- cell physiology
- chronic infection
- defined minimal medium
- enterotoxin
- enterotoxins
- Enzymes
- erianin
- Eye
- Fermentation
- gene regulation
- HACCP
- HigBA
- in vivo models
- Infection
- inhibitor
- innate immunity
- Leukocidin
- low cytotoxic strains
- LukAB
- LukGH
- lux fusion
- mastitis
- methicillin-resistant Staphylococcus aureus
- microbiome
- molecular mechanism
- mouse abscess
- n/a
- pathogenicity islands
- polyclonal antibody
- PPIase
- PpiB
- PrsA
- PSMs
- S. aureus
- sortase A
- sphingomyelin
- staphylococcal enterotoxin
- Staphylococcus aureus
- superantigen
- superantigen-like protein
- toxin neutralization
- toxin-antitoxin systems
- toxins
- toxoid vaccine
- virulence factor
Links
DOI: 10.3390/books978-3-03921-426-6Editions
