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Micro- and Nanofluidics for Bionanoparticle Analysis
Yong Zeng and Xuanhong Cheng
2019
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Bionanoparticles such as microorganisms and exosomes are recoganized as important targets for clinical applications, food safety, and environmental monitoring. Other nanoscale biological particles, includeing liposomes, micelles, and functionalized polymeric particles are widely used in nanomedicines. The recent deveopment of microfluidic and nanofluidic technologies has enabled the separation and anslysis of these species in a lab-on-a-chip platform, while there are still many challenges to address before these analytical tools can be adopted in practice. For example, the complex matrices within which these species reside in create a high background for their detection. Their small dimension and often low concentration demand creative strategies to amplify the sensing signal and enhance the detection speed. This Special Issue aims to recruit recent discoveries and developments of micro- and nanofluidic strategies for the processing and analysis of biological nanoparticles. The collection of papers will hopefully bring out more innovative ideas and fundamental insights to overcome the hurdles faced in the separation and detection of bionanoparticles.
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Keywords
- 3-ethenylpyridine
- ballpoint pen printing
- biomarker detection
- cancer metastasis
- cell isolation
- circulating tumour cells (CTCs)
- COMSOL
- conductive electrode
- crop disease
- cross-flow filtration
- dielectric film
- digital microfluidic chip
- digital microfluidic device
- droplet actuation
- electrowetting
- ferrofluids
- flow control
- flow focusing
- fluorescence
- HIV diagnostics
- Image processing
- lensfree
- light diffraction
- lipid nanoparticles
- magnetic field
- microfluidic
- microfluidic device
- microfluidic systems
- Microfluidics
- microparticles
- multi-step assay
- n/a
- nanoparticle characterization
- nanoporous membrane
- online analysis
- optically induced dielectrophoresis (ODEP)
- oxidized hollow mesoporous carbon nanosphere
- paper-based microfluidic device
- plastic wrap
- plug flow mixer
- precipitation
- second-hand smoke
- single particle analysis
- surface acoustic wave