Gastrointestinal Variables and Drug Absorption
0 Ungluers have Faved this Work
Login to Fave
This book presents some of the state-of-the-art methods for the study of the gastrointestinal variables affecting oral drug absorption. Practical applications of new in vitro release/dissolution methods are presented, as well as in vitro permeability studies to explore segmental differences. The application of MRI methods for the study of colon physiology is presented to illustrate its potential applications in controlled release dosage form design. Some examples of successful in vitro–in vivo correlations show how implementing the gastrointestinal physiological variables in the new in vitro methods can improve the predictions of in vivo drug product performance. The book contains an updated review of the experimental, computational, and in vivo approaches for measuring intestinal permeability.
This book is included in DOAB.
Why read this book? Have your say.
You must be logged in to comment.
Rights InformationAre you the author or publisher of this work? If so, you can claim it as yours by registering as an Unglue.it rights holder.
This work has been downloaded 221 times via unglue.it ebook links.
- 173 - pdf (CC BY-NC-ND) at Unglue.it.
- Biopharmaceutics Classification System (BCS)
- biorelevant media
- butyric acid
- colon delivery
- colon microbiota
- controlled release formulations
- experimental and computational permeability methods
- gastrointestinal absorption
- gastrointestinal drug release
- gastrointestinal simulator
- gellan gum
- in situ single-pass perfusion
- in vitro dissolution
- in vitro systems
- in vitro–in vivo correlation (IVIVC)
- in vivo
- intestinal drug absorption
- intestinal permeability
- ionotropic gelation
- large bowel
- large intestine
- lipid-based formulations
- liquid–liquid phase separation
- Magnetic Resonance Imaging
- mathematical modeling
- microscopy imaging
- modeling study
- oral absorption
- polymer/clay composite
- poorly water-soluble drugs
- regional absorption
- regional drug absorption
- Ussing chamber
Copy/paste this into your site: