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Synthetic and Biosynthetic Approaches to Marine Natural Products
Asunción Barbero
2020
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Marine natural products containing a heterocyclic moiety in their structure are present in a wide variety of sponges, corals, algae, and fungi. Many of them show important biological activities such as cytotoxic properties against several cancer cell lines. Their challenging chemical structures have attracted the attention of many researchers who have developed various synthetic approaches. This Special Issue presents some examples of new synthetic or biosynthetic methodologies to access this type of marine natural drug.
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Keywords
- ?-ketoacyl ACP Synthase
- acid mediated cyclization
- alotamide
- antarctic-derived fungus
- anticandidal activity
- anticonvulsant
- antidepressant
- antimicrobial peptides
- antiproliferative activity
- antitumor
- astaxanthin
- asymmetric synthesis
- benzo[d]thiazol
- biological activity
- Candida albicans
- Cladosporium sphaerospermum
- cyclogeranylsulfonylbenzene isomers
- dihydropallescensin 2
- functional-analogues
- furanosesquiterpenes
- GGPPS
- Haematococcus pluvialis
- hybrid PKS-NRPS
- hybrid polyketides
- Iso-Seq
- isomicrocionin-3
- lipase-mediated resolution
- LLC-PK1 cells
- marine drugs analogues
- marine hydroquinone
- marine natural product
- Marine Natural Products
- medicine
- Microalgae
- MM cell line
- natural compound analogues
- Octominin
- Octopus minor
- pallescensin 1
- pallescensin 2
- pallescensone
- peptide/polyketide molecules
- psammaplin A
- relative structural determination
- Short Chain Fatty Acids
- smenamides
- stereoselective
- stereoselective synthesis
- structural modification
- Synechococcus sp. PCC 7942
- Synthesis
- synthetic analogues
- tetrahydropyrans
- tetramic acid
- thymoquinone
- toluquinol
Links
DOI: 10.3390/books978-3-03928-467-2Editions
