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Polymeric Systems as Antimicrobial or Antifouling Agents
Antonella Piozzi and Iolanda Francolini
2020
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The rapid increase in the emergence of antibiotic-resistant bacterial strains, combined with a dwindling rate of discovery of novel antibiotic molecules, has created an alarming issue worldwide. Although the occurrence of resistance in microbes is a natural process, the overuse of antibiotics is known to increase the rate of resistance evolution. Under antibiotic treatment, susceptible bacteria inevitably die, while resistant microorganisms proliferate under reduced competition. Therefore, the out-of-control use of antibiotics eliminates drug-susceptible species that would naturally limit the expansion of resistant species. In addition, the ability of many microbial species to grow as a biofilm has further complicated the treatment of infections with conventional antibiotics. A number of corrective measures are currently being explored to reverse or slow antibiotic resistance evolution, Among which one of the most promising solutions is the development of polymer-based antimicrobial compounds. In this Special Issue, different polymer systems able to prevent or treat biofilm formation, including cationic polymers, antibacterial peptide-mimetic polymers, polymers or composites able to load and release bioactive molecules, and antifouling polymers able to repel microbes by physical or chemical mechanisms are reported. Their applications in the design and fabrication of medical devices, in food packaging, and as drug carriers is investigated.
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Keywords
- 2-hydroxyethyl methacrylate
- 3D printing
- ?-chymotrypsin
- Acinetobacter baumannii
- acrylates
- active packaging
- additive manufacturing
- additives
- Adhesives
- amorphous materials
- anti-biofilm surface
- anti-biofilm surfaces
- antibacterial
- Antibacterial activity
- antibacterial peptides
- antibacterial polymers
- antibacterial properties
- antibiofilm activity
- antifouling
- antifouling materials
- antimicrobial peptide
- antimicrobial peptides
- antimicrobial polymer
- antimicrobial polymers
- antimicrobial properties
- antimicrobial resistance
- bacteria viability
- bactericidal coatings
- biocompatible polymer
- biocompatible systems
- Biofilm
- biofilm analysis
- biofilm devices
- biofilm methods
- biofilm on contact lenses
- bionanocomposites
- cationic polymers
- circular dichroism
- coatings from nanoparticles
- coatings wettability
- composites
- copolymerization
- copper paint
- cuprous oxide nanoparticles
- drug carrier
- Drug delivery
- Drug delivery systems
- dynamic light scattering
- Escherichia coli
- ESKAPE pathogens
- fluorescence
- food shelf-life
- foodborne pathogens
- halictine
- hemolytic activity
- imidization
- Infrared spectroscopy
- layered double hydroxides
- linear low-density polyethylene
- lipopeptides
- medical device-related infections
- microbial biofilm
- microbicidal coatings
- multidrug-resistant
- multifunctional hybrid systems
- n/a
- ocular infections
- olive mill wastewater
- ordered mesoporous silica
- periodontal biofilms
- periodontitis
- persister cells
- physiological salt
- plastic materials
- polyamide 11
- polyethylene glycol
- polymeric biocide
- polymeric films
- polymeric surfaces
- polymerizable quaternary ammonium salts
- Polymers
- proteinase
- quaternary ammonium
- quaternary ammonium salts
- quaternization
- segmented polyurethanes
- sol-gel preparation
- Staphylococcus aureus
- Surface functionalization
- Thermal stability
- UV-induced polymerization
- water disinfection
- wound dressings
Links
DOI: 10.3390/books978-3-03928-457-3Editions
