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Organs-on-chips
Yu-suke Torisawa and Yi-Chung Tung
2020
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Recent advances in microsystems technology and cell culture techniques have led to the development of organ-on-chip microdevices that produce tissue-level functionality, not possible with conventional culture models, by recapitulating natural tissue architecture and microenvironmental cues within microfluidic devices.
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Keywords
- 3D cell culture
- 3D cell culture system
- Angiogenesis
- barrier permeability
- beating force
- bio-mechanical property
- Biomechanics
- biomimetic oxidation
- cardiac 3D tissue
- cell
- Cell culture
- compression
- drug absorption
- drug efficacy
- drug hepatotoxicity
- drug metabolism
- endothelial cell activation
- epithelial–endothelial interface
- fluoroelastomer
- functional neuron imaging
- High-Throughput Screening
- History of engineering & technology
- human induced pluripotent Stem cell-derived cardiomyocytes (hiPS-CM)
- image-based screening
- integrated pump
- ischemia/reperfusion injury
- lattice light-sheet microscopy
- liver-on-a-chip
- lung epithelial cell
- mechanical cue
- membranes
- MEMS
- microfabrication
- microfluidic device
- Microfluidics
- multi-culture
- n/a
- nanogrooves
- neuronal cell networks
- neuronal cells
- neuronal guidance
- organ-on-a-chip
- organ-on-a-chip (OOC)
- organ-on-chip
- organ-on-chips
- organoid
- organs-on-chips
- paracellular/transcellular transport
- passive delivery
- PDMS
- SH-SY5Y cells
- shear flow
- shear stress
- Silicon
- spheroid array
- strain
- Stress
- stretch
- surfactant protein
- syringe pump
- Technology, engineering, agriculture
- Technology: general issues
- thrombolysis
- Tissue Engineering
- trans-epithelial electrical resistance
- vacuum chuck
- vascularization
- vascularized tumor model
- vessel branching
Links
DOI: 10.3390/books978-3-03928-918-9Editions
