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Biomaterials for Bone Tissue Engineering
José A. Sanz-Herrera
2020
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Bone tissue engineering aims to develop artificial bone substitutes that partially or totally restore the natural regeneration capability of bone tissue lost under circumstances of injury, significant defects, or diseases such as osteoporosis. In this context, biomaterials are the keystone of the methodology. Biomaterials for bone tissue engineering have evolved from biocompatible materials that mimic the physical and chemical environment of bone tissue to a new generation of materials that actively interacts with the physiological environment, accelerating bone tissue growth. Mathematical modelling and simulation are important tools in the overall methodology. This book presents an overview of the current investigations and recent contributions in the field of bone tissue engineering. It includes several successful examples of multidisciplinary collaboration in this transversal area of research. The book is intended for students, researchers, and professionals of a number of disciplines, such as engineering, mathematics, physics, chemistry, biomedicine, biology, and veterinary. The book is composed of an editorial section and 16 original research papers authored by leading researchers of this discipline from different laboratories across the world
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Keywords
- 3D virtual surgical plan
- 3D-printed implant
- additive manufacturing
- Adipogenesis
- automatic segmentation
- bioelectromagnetism
- biomaterial applications
- Biomaterials
- Biomechanics
- bone adaptation
- Bone Marrow
- bone morphogenesis proteins
- Bone Regeneration
- bone tissue
- bone tissue engineering
- bone tissue regeneration
- bone tumor
- cartilage
- computational fluid dynamics
- computational mechanics
- computational mechanobiology
- computational modelling
- Computed Tomography
- cone beam computed tomography
- Cortical bone
- critical size defect
- culturing protocol
- damage
- dental implants
- digital image correlation
- direct current electric field
- elastoplasticity
- electric stimulation
- electrically active implants
- Finite element
- finite element analysis
- Finite element method
- finite element modelling
- Finite elements
- finite-element simulation
- Fixation design
- fracture risk
- human dental pulp stem cells
- Lagrangian scalar tracking
- Lattice Boltzmann method
- loose sintering
- mass transfer
- maxillofacial
- mechanical behaviour
- micromechanics
- minipig
- MSCs
- multiscale analysis
- musculoskeletal modelling
- n/a
- numerical methods in bioengineering
- numerical results
- optimization
- osseointegration
- osteo-differentiation
- osteoporosis
- Otsu’s method
- oxygen delivery
- Pelvis
- powder metallurgy
- prediction marker
- resonance frequency analysis
- scaffold design
- selective laser melting
- sliding window
- spark plasma sintering
- stem cell
- substrate-mediated electrical stimulation
- Ti6Al4V scaffolds
- Titanium
- trabeculae
- trabecular bone score
- transport
- triply periodic minimal surfaces
- vertebra
- Von Mises stress
- wollastonite
- Xenografts