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Virus-Like Particle Vaccines
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The structure, uniformity, stability, and functions of virus-like particles (VLPs) have encouraged scientists to utilize them as a unique tool in various applications in biomedical fields. Their interaction with the innate immune system is of major importance for the adaptive immune response they induce. The innate immune cells and molecules recognize and interact with VLPs on the basis of two major characteristics: size and surface geometry. VLP-based vaccines against hepatitis B, human papilloma, malaria, and hepatitis E have been developed and are available in many countries around the world. Given the inherent immunogenicity of VLPs, they render themselves ideal for the development of new vaccines against infectious diseases as well as noncommunicable diseases, such as chronic inflammation or cancer. This Special Issue is designed to provide an up-to-date view of the latest progress in the development of VLP-based prophylactic and therapeutic vaccines and technologies for their generation.
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Keywords
- Antibodies
- antibody titers
- antigen
- antigen display
- antigenic analysis
- avian flu
- blocking antibodies
- Cancer
- capsid
- cat allergy
- cross-reactivity
- cryo-TEM
- Cytomegalovirus
- epitope
- epitope characterization
- Fel d 1
- flow virometry
- genotype
- H7N9
- HCMV
- hepatitis B virus
- hepatitis E vaccine
- horse
- HPVs
- Humanities
- HypoCat™
- IAV
- IL-13
- Immune response
- Immunotherapy
- influenza A(H1N1)pdm09
- interleukin-13
- long-lived plasma cells
- Mice
- minor capsid protein (L2)
- multivalency
- n/a
- nanoparticle
- Norovirus
- NTA
- original antigenic sin (OAS)
- pandemic influenza A
- plant virus
- platform
- pre-existing immunity
- Pregnant women
- purified IgG
- SEM
- serological evaluation
- Social interaction
- Social issues & processes
- Society & culture: general
- Society & Social Sciences
- SRFM
- sub-viral particle
- Sudan virus
- surface (envelope) antigen
- Tfh cells
- thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues
- thema EDItEUR::N History and Archaeology::NH History
- vaccination
- Vaccine
- vaccine platform
- Vaccines
- viral quantification
- virion-like epitopes
- virus-like
- virus-like particle
- virus-like particles
- virus-like particles (VLPs)
- VLP
- VLP vaccine
- well-characterized vaccines
Links
DOI: 10.3390/books978-3-03943-075-8Editions