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Modern Strategies for Heterocycle Synthesis
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Heterocycles feature widely in natural products, agrochemicals, pharmaceuticals and dyes, and their synthesis is of great interest to synthetic chemists in both academia and industry. The contributions of recent applications of new methodologies in C–H activation, photoredox chemistry, cross-coupling strategies, borrowing hydrogen catalysis, multicomponent and solvent-free reactions, regio- and stereoselective syntheses, as well as other new, attractive approaches for the construction of heterocyclic scaffolds are of great interest. This Special Issue is dedicated to featuring the latest research that is ongoing in the field of heterocyclic synthesis. It is expected that most submissions will focus on five- and six-membered oxygen and nitrogen-containing heterocycles, but structures incorporating other rings/heteroatoms will also be considered. Original research (communications, full papers and reviews) that discusses innovative methodologies for assembling heterocycles with potential application in materials, catalysis and medicine are therefore welcome.
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Keywords
- 1,2,3-triazol
- 1,3-oxazines
- 1-oxa-triene
- 1H-imidazole-2(3H)-thione
- 2H-pyran
- 3,2′:6′,3″-terpyridine
- 3-trifluoroacetyl coumarins
- 4-bromo quinolines
- 5-acylamino-1,3-thiazoles
- acylhydrazone group
- alkynes
- alkynoic acids
- amine nucleophiles
- antifungal activities
- antitumor
- aromatic substitution
- arylation
- asymmetric dimeric β-carboline
- aza-Wittig
- azides
- cascade cyclization
- cascade reaction
- CF3CO-acetylenes
- cinnolines
- click reaction
- condensation
- copper-catalyzed azide-alkyne cycloaddition
- coumarin
- CuAAC
- cyclic ethers
- cycloalkynes
- cyclohexanol derivative
- cycloisomerization
- Cytotoxic
- Cytotoxicity
- dienone
- dihydrocoumarins
- enol ethers
- fluorescence
- fluorinated heterocycles
- fluoroalcohol
- fused N-heterocycles
- gold catalysis
- Hantzsch reaction
- heterocycles
- heterocyclic
- inter-molecular approach
- intra-molecular approach
- ketone
- Knoevenagel
- medicine
- multicomponent reaction
- multicomponent reactions
- n/a
- Natural Products
- nucleobase
- organic dyes
- organocatalysis
- oxa-electrocyclization
- phenols
- photocatalysis
- photoredox
- photoredox cyclization
- propargyl Claisen
- propargylic alcohols
- purine
- pyrazolo[3,4-b]pyridine
- pyridine
- pyrrolidones
- Richter cyclization
- saturated oxygen heterocycles
- silica sulfuric acid
- Solid-phase synthesis
- Staudinger reaction
- structure–activity relationship
- Suzuki coupling
- Synthesis
- synthesis of benzofurans
- terpyridines
- TMSBr
- total synthesis
- traceless synthesis
- triazoles
- triazolylmethyl phosphate
- triazolylmethyl phosphinate
- valence isomerism
- visible-light-induced catalysis
- α-chloroglycinates
- α-halohydrazones
- γ-lactam
Links
DOI: 10.3390/books978-3-0365-0341-7Editions