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From Basic Research to New Tools and Challenges for the Genotoxicity Testing of Nanomaterials

From Basic Research to New Tools and Challenges for the Genotoxicity Testing of Nanomaterials

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This Special Issue presents studies on the genotoxicity of nanomaterials. Although nanomaterials provide multiple benefits in a wide range of applications, challenges remain in addressing strong concerns about their risks to the environment and human health. As a result of inconsistencies among published results and diverging conclusions, the understanding of nanomaterial exposure and toxicity remains unclear. Determining whether these materials cause DNA damage—the first step in carcinogenesis—must be a priority in testing. In this book, readers will find recent publications on the genotoxic response to a broad range of nanomaterials, the impact of physico-chemical characteristics, safe-by-design and new developed tools.

This book is included in DOAB.

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Keywords

  • 3D culture
  • advanced in vitro model
  • AgNP
  • Allium cepa
  • Aluminum
  • antioxidant activity
  • Apoptosis
  • BEAS-2B cells.
  • CeO2NP
  • comet assay
  • Cytotoxic
  • Cytotoxicity
  • DNA Damage
  • DNA Methylation
  • epigenetics
  • FPG enzyme
  • genotoxic
  • genotoxicity
  • graphene oxide
  • gut
  • hepatotoxicity
  • HepG2
  • high throughput screening
  • Hprt
  • Hs27 human fibroblasts
  • human amniotic cells
  • Humanities
  • in vitro genotoxicity
  • in vitro testing
  • lincomycin
  • Liver
  • liver spheroids
  • metal oxides
  • metal/coating agent ratio
  • micronuclei formation
  • micronucleus
  • micronucleus assay
  • multi-walled carbon nanotubes (MWCNT)
  • n/a
  • nanomaterial
  • Nanoparticles
  • nanoplastics
  • nanotoxicology
  • nongenotoxic silver nanoparticles
  • oral route
  • Oxidative Stress
  • polystyrene nanoparticles
  • reduced graphene oxide
  • safer-by-design
  • silver ions
  • SiO2NP
  • Social interaction
  • Social issues & processes
  • Society & culture: general
  • Society & Social Sciences
  • TiO2NP
  • titanium dioxide nanoparticles
  • tritiated particles
  • tungsten
  • V79 cells
  • ZnONP

Links

DOI: 10.3390/books978-3-0365-0113-0

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