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Peptides for Health Benefits 2019
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In recent years, peptides have received increased interest from the pharmaceutical industry. The high potency, specificity, and safety profile are the main strengths of bioactive peptides as new and promising therapies that may fill the gap between small molecules and protein drugs. These positive attributes have renewed interest in the discovery, optimization, and development of peptides as pharmacological therapy. Among bioactive peptides, those released from food sources have acquired importance as nutraceutical and active components in functional foods because they possess regulatory functions that can lead to health benefits. This Special Issue covers a selection of recent research papers and reviews in the field of bioactive peptides. It covers all aspects of peptide research in relation to health promotion. In particular, it emphasizes current knowledge and research trends concerning bioactive peptides, including identification and quantification of peptides from new sources, methods for their production and purification, structure–function relationships, mechanisms of action, in vitro and in vivo assays for the evaluation of their bioactivity, physiological evidence to support health benefits, and peptide stability and bioavailability. Papers regarding the development of new drugs, functional foods, or nutraceuticals based on bioactive peptides were also considered.
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Keywords
- ACE-inhibitory activity
- acrylamide
- airway inflammation
- alcalase hydrolysate
- Alzheimer’s disease
- AMD
- AMP identification and design
- amyloid
- amyloid fibrils
- and endothelial regeneration
- angiogenic precursor cells
- angiotensin I converting enzyme
- anti-biofilm peptides
- anti-inflammatory
- antibiotic resistance
- antifungal activity
- antigen-specific
- antihypertensive peptides
- antimicrobial peptide
- antimicrobial peptides
- antimicrobial peptides (AMPs)
- antimicrobial resistance
- antioxidant activity
- antioxidant peptide
- antiproliferative assay
- antisepsis, peptide antibiotics
- apolipoprotein E
- Arthritis
- Asthma
- Aβ peptide
- bioactive peptide
- bioactive peptides
- Biology, Life Sciences
- biomarkers
- BIOPEP-UWM database
- biosynthesis
- bone erosion
- cancer antigen
- cancer stem cells
- cartilage destruction
- cathelicidins
- Cec-analogs
- Cecropins
- Central Nervous System Diseases
- chemoprevention
- Chlorella sorokiniana
- chronic diseases
- Clostridioides difficile
- CNV
- collagen
- collagen peptide
- colorectal cancer
- combinatorial library
- confocal microscopy
- conjugation
- Copper
- Crassostrea angulata
- cryptides
- CXCR3
- cystic fibrosis
- cytoprotective effect
- Database
- defensins
- Diseases
- docetaxel
- doxorubicin
- dry-cured pork ham
- dyslipidemia
- endothelial dysfunction
- endothelial progenitor cells
- Energy Expenditure
- enteric nervous system
- enzyme
- extra domain B
- Fermentation
- fetal bovine serum (FBS)
- fibroblasts
- fibronectin
- Fmoc/tBu
- food intake regulation
- food-derived
- Foods
- formyl peptide receptors
- FPYLRH
- fresh tissue
- Functional Food
- Galanin
- gender differences
- Glioma
- GPR10
- Histatin-5
- host defense peptides
- Hs02
- human antimicrobial peptides
- human keratinocytes
- humanized mouse
- hybrid peptide
- hydrolysis
- hydroxyprolyl-glycine (Hyp-Gly)
- hyperglycemia
- Hypertension
- immune checkpoint inhibitor
- Immune response
- immune suppression
- immunomodulant
- in silico
- In situ tetramer staining
- Inflammation
- inflammatory bowel disease
- Insects
- intragenic antimicrobial peptide
- Lactoferricin B (Lfcin B)
- library design
- Ligands
- lunasin
- Mathematics & science
- MDA
- MDR infectious diseases
- membrane activity
- MHC tetramer
- migration
- miiuy croaker (Miichthys miiuy)
- mode of action
- molecular blind docking
- molecular docking
- molecular weight
- monocyte
- MRSA
- multimeric peptides
- mutagenesis
- n/a
- nano liquid chromatography tandem mass spectrometry (nanoLC–nanoESI MS/MS)
- Neuroprotection
- Neurotensin
- NF-κB
- non-atopic asthma
- Nutraceuticals
- Nutrition
- Obesity
- oral delivery
- osteostatin
- Oxidative Stress
- pegylated glucagon-like peptide 1
- peptide
- peptide vaccine
- peptide–drug conjugate
- physico-chemical properties
- PI3K/Akt pathway
- pidotimod
- pig
- piscidins
- platelets
- polymicrobial biofilms
- pro-inflammatory
- pro-inflammatory cytokines
- prolactin-releasing peptide
- prolyl-hydroxyproline (Pro-Hyp)
- prostate cancer
- protection ability
- proteolysis
- proteome microarray
- Proteomics
- pseudin-2
- Pseudomonas aeruginosa
- pulmonary emphysema
- Reference, information & interdisciplinary subjects
- Research & information: general
- RF-amide peptides
- Rheumatic Diseases
- screening
- sheepskin
- signaling
- Sjögren’s syndrome
- SMILES code
- Solid-phase synthesis
- sPLA2
- Staphylococcus aureus
- Stomach
- swim bladder
- synergistic effects
- synergy
- T cell
- T cells
- targeting
- temporin
- therapeutic potential
- Type 1 Diabetes
- vasoactive intestinal peptide
- VEGFR1
- velvet antler
- VPAC1 receptor
- VPAC2 receptor
- whey peptides
- Αβ oligomer
Links
DOI: 10.3390/books978-3-03936-081-9Editions