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Nanobodies have become outstanding tools for biomedical research, diagnostics and therapy. Recent advances in the identification and functionalization of target-specific nanobodies now make nanobody-based approaches broadly available to many researches in the field. This book provides a compilation of original research articles and comprehensive reviews covering important and up to date aspects of research on nanobodies and their applications for immunoassays, proteomics, protein crystallization and in vitro and in vivo imaging.
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Keywords
- AIDS
- anti-cytokine therapy
- antibody
- autoimmune disease
- Bacillus anthracis
- Beta galactosidase
- bi-specific VHH
- biodefense
- blood–brain barrier
- brain imaging
- BRET
- c-Met
- C. elegans
- camelid
- Cancer
- cellular models
- chromobodies
- co-crystallisation
- competition studies
- compound screening
- Delivery
- Development
- Drosophila
- epitope mapping
- Fc-domain
- fluorescent
- Formatting
- genetic fusion
- GFP
- GTPase RHO
- half-life
- hemagglutinin
- hepatocyte growth factor receptor
- HGFR
- HIV
- hydrogen exchange-mass spectrometry
- imaging
- immunoassay
- Immunotherapy
- Influenza
- influenza B virus
- intrabody
- intracellular antibody
- intraoperative imaging
- ischemia
- live-cell imaging
- llama
- Llama Antibodies
- MagPlex
- MCAO
- medicine
- Met
- Molecular imaging
- molecular therapy
- n/a
- nanobodies
- nanobody
- NanobodyTM
- Neurodegenerative Diseases
- nuclear imaging
- P-type ATPase
- pepscan
- phage display
- photosensitizer
- Ras
- sensor
- single domain antibodies
- Single Domain Antibody
- single-domain antibodies
- single-domain antibody
- single-domain antibody fragments
- Stroke
- targeted fluorescence imaging
- targeted photodynamic therapy
- TNF
- toxin
- Vaccine
- VHH
- virus
- Western equine encephalitis virus
- yeast display
- Zebrafish
- Zinc-transport
- Zinc-transporting P-ATPase
- ZntA
Links
DOI: 10.3390/books978-3-0365-0379-0Editions