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Microbial Virulence Factors
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Microbial virulence factors encompass a wide range of molecules produced by pathogenic microorganisms, enhancing their ability to evade their host defenses and cause disease. This broad definition comprises secreted products such as toxins, enzymes, exopolysaccharides, as well as cell surface structures such as capsules, lipopolysaccharides, glyco- and lipoproteins. Intracellular changes in metabolic regulatory networks, governed by protein sensors/regulators and non-coding regulatory RNAs, are also known to contribute to virulence. Furthermore, some secreted microbial products have the ability to enter the host cell and manipulate their machinery, contributing to the success of the infection. The knowledge, at the molecular level, of the biology of microbial pathogens and their virulence factors is central in the development of novel therapeutic molecules and strategies to combat microbial infections. The present collection comprises state of the art research and review papers on virulence factors and mechanisms of a wide range of bacterial and fungal pathogens for humans, animals, and plants, thus reflecting the impact of microorganisms in health and economic human activities, and the importance of the topic.
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Keywords
- 5637 bladder cells
- Actin
- actin proteolysis
- Actinomycetales
- Aeromonas hydrophila
- anti-virulence
- antibiotic resistance
- antimicrobial peptide
- antimicrobial peptides
- Apple
- apple proliferation
- autotransporter
- Bacteria
- bacterial invasion
- bacterial pathogens
- bacterial surface protein
- Biofilm
- Biofilm formation
- Biology, Life Sciences
- blood–brain barrier
- blood–cerebrospinal fluid barrier
- Bordetella pertussis
- Burkholderia cepacia complex
- Candida
- Candida albicans
- chronic infection
- Citrobacter
- coagulase-negative staphylococci
- complement
- compound appressorium
- covalent labeling
- cystic fibrosis
- Cytotoxicity
- Dickeya solani
- differential expression proteins
- EDTA
- effector protein
- Enterobacter
- Enterobacterales
- fluconazole
- Fungal pathogens
- fungicidal activity
- Gelatin
- Gene expression
- global regulator
- grimelysin
- Hfq
- host-pathogen interaction
- hyphae
- Immune Evasion
- Immune response
- Infection
- Inflammation
- inter-kingdom protection
- interspecies interactions
- intracellular survival
- Klebsiella
- lon expression
- LysR-family
- Manipulation
- Mathematics & science
- meningitis
- metalloproteinases
- microbial virulence factors
- Morphology
- motility
- mucin
- omics analysis
- outer membrane vesicles (OMVs)
- Oxidative Stress
- pathogenicity
- pathogenomics
- pectinolytic enzymes
- Persistence
- phytoplasma
- plant pathogen
- primary ciliary dyskinesia
- protealysin
- protease ECP 32
- protease Lon
- proteomics analysis
- Pseudomonas aeruginosa
- pyolysin
- Reference, information & interdisciplinary subjects
- replicative niche
- Research & information: general
- resistance to stress
- Salmonella enterica serovar Typhimurium
- Sclerotinia sclerotiorum
- serine proteases
- serum resistance
- small noncoding regulatory RNAs
- solute-binding proteins
- SPATEs
- sputum
- SpyCatcher
- SsNsd1
- T3SS
- topology mapping
- truA
- Trueperella pyogenes
- two-dimensional electrophoresis
- type III secretion system
- usg
- UTIs
- Virulence
- virulence factor
- Virulence Factors
- whole genome sequencing
- ΔlahS
Links
DOI: 10.3390/books978-3-03936-947-8Editions