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Oxidative Stress in Diabetic Retinopathy

Oxidative Stress in Diabetic Retinopathy

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The combination of an increasing prevalence of diabetes and the aging of populations enables the appearance of a greater number of associated complications such as diabetic retinopathy. Diabetic retinopathy is the leading cause of preventable vision loss in working-age adults. The objective of this Special Issue is to highlight the existing evidence regarding the relationship between oxidative stress and low-grade chronic inflammation induced by hyperglycemia with the development and progression of diabetic retinopathy, with an emphasis on the importance of early diagnosis and the use of antioxidant and anti-inflammatory approaches to prevent or delay the harmful effects of diabetes on retinal tissue.

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Keywords

  • Aging
  • Angiogenesis
  • antioxidant
  • Antioxidants
  • Apoptosis
  • aqueous humor
  • ascorbic acid
  • astaxanthin
  • biomarkers
  • biomarkers of diabetic retinopathy
  • blood-retinal barrier
  • carotenoid
  • Cinnamomi Ramulus
  • CPA4-1
  • cyclooxygenase
  • Cytochrome P450
  • db/db mice
  • Diabetes Mellitus
  • diabetic retinopathy
  • diabetic retinopathy (DR)
  • docosahexaenoic acid (DHA)
  • Eicosanoids
  • eicosapentaenoic acid (EPA)
  • epiretinal membrane
  • extracellular vesicles
  • fenofibrate
  • free radicals
  • GLP-1
  • glycation
  • glyoxalase
  • HDAC6
  • high-mobility group box 1 (HMGB1)
  • human retina
  • hyperglycemia
  • Inflammation
  • inflammatory pathways
  • internal limiting membrane
  • lipoxygenase
  • macular hole
  • medicine
  • metabolic memory
  • miRNA
  • Mitochondria
  • n/a
  • novel therapies
  • Nrf2
  • occludin
  • Oxidative Stress
  • Paeoniae Radix
  • photoreceptor
  • photoreceptor cells
  • PI3K
  • proliferative diabetic retinopathy
  • Reactive Oxygen Species
  • redox
  • Retinal disease
  • retinal endothelial cell senescence
  • retinal endothelial cells
  • retinal pigment epithelium
  • superoxide dismutase
  • tear film
  • thioredoxin
  • tubastatin A
  • Vitamin D
  • vitreoretinal surgery
  • vitreous humor

Links

DOI: 10.3390/books978-3-0365-0449-0

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