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Male Germline Chromatin
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Spermatogenesis requires radical restructuring of germline chromatin at multiple stages, involving coordinated waves of DNA methylation/demethylation, histone modification, and the replacement and removal that occurs before, during, and after meiosis. This Special Issue will draw together papers that address all aspects of chromatin organization and dynamics in the male germ line, in humans, and in model organisms. In particular, we will invite authors to discuss novel methods for studying germline chromatin structure, the interplay between chromatin structure and susceptibility to DNA damage and mutation, chromatin modifications associated with epigenetic inheritance in the early embryo, and the impact this work has for understanding natural fertility and improving assisted reproduction techniques.
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Keywords
- assisted reproduction
- Biology, Life Sciences
- centromeres
- Chromatin
- chromatin remodeling
- chromosome associations
- chromosome organization
- chromosome painting
- chromosome territories
- chromosome translocation
- Chromosomes
- DNA double-strand breaks
- DNA fragmentation
- DNA oxidation
- epigenetic inheritance
- genetic instability
- histone retention
- implantation
- In vitro fertilisation
- Infertility
- male germ cells
- Male Infertility
- Mathematics & science
- meiotic prophase
- miscarriage
- morphometrics
- mouse
- mouse sperm chromatin
- Mus m. domesticus
- Mutations
- NOR
- nuclear organisation
- nuclear organization
- nuclear-3D-parameters
- nucleoli
- Oxidative Stress
- Reactive Oxygen Species
- Reference, information & interdisciplinary subjects
- reproductive aging
- Research & information: general
- Robertsonian chromosomes
- SLY
- sperm
- sperm DNA damage
- spermatocytes
- Spermatogenesis
- spermatozoa
- spermiogenesis
- telomeres
- testis
- Y Chromosome
Links
DOI: 10.3390/books978-3-03936-855-6Editions