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Advanced Materials in Drug Release and Drug Delivery Systems
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Development of new drug molecules is costly and requires longitudinal, wide-ranging studies; therefore, designing advanced pharmaceutical formulations for existing and well-known drugs seems to be an attractive device for the pharmaceutical industry. Properly formulated drug delivery systems can improve pharmacological activity, efficacy and safety of the active substances. Advanced materials applied as pharmaceutical excipients in designing drug delivery systems can help solve problems concerning the required drug release—with the defined dissolution rate and at the determined site. Novel drug carriers enable more effective drug delivery, with improved safety and with fewer side effects. Investigations concerning advanced materials represent a rapidly growing research field in material/polymer science, chemical engineering and pharmaceutical technology. Exploring novel materials or modifying and combining existing ones is now a crucial trend in pharmaceutical technology. Eleven articles included in the the Special Issue “Advanced Materials in Drug Release and Drug Delivery Systems” present the most recent insights into the utilization of different materials with promising potential in drug delivery and into different formulation approaches that can be used in the design of pharmaceutical formulations.
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Keywords
- 3D matrix
- 3D printing
- amorphization
- Bicalutamide
- Biocompatibility
- capsules
- cellular targets
- cellulose derivative
- CO administration
- CO kinetic profile
- CO-releasing materials
- CO-releasing molecules
- dissolution rate
- Drug delivery
- drug release
- drug-eluting stents
- electrospinning
- ethylcellulose
- Films
- FITC-peptide
- fused deposition modeling
- gastro-resistant
- Gelatin
- GQDs
- heme oxygenase
- host-guest interaction
- hot-melt extrusion
- hyaluronic acid
- hydrogel
- immobilization of drug
- in vivo
- itraconazole
- layer-by-layer
- Macrogol 6000
- mesoporous silica
- microparticles
- microspheres
- mPEG-PLA
- multilayer film
- n/a
- optical-magneto nanoparticles
- organometallic complexes
- orodispersible minitablets
- pathological role
- pharmaceutical drugs
- pharmaceutical excipient
- pharmacokinetic functions
- Poloxamer® 407
- polycaprolactone
- polymer
- polymeric material
- real-time tracking
- rupatadine fumarate
- sirolimus
- solid dispersions
- solid dosage forms
- spray drying
- Structure
- supercritical carbon dioxide
- taste masking
- Technology, engineering, agriculture
- Technology: general issues
- therapeutic agent
- total alkaloids from Alstonia scholaris leaves
Links
DOI: 10.3390/books978-3-0365-1059-0Editions