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Recent Developments in Cancer Systems Biology
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This ebook includes original research articles and reviews to update readers on the state of the art systems approach to not only discover novel diagnostic and prognostic biomarkers for several cancer types, but also evaluate methodologies to map out important genomic signatures. In addition, therapeutic targets and drug repurposing have been emphasized for a variety of cancer types. In particular, new and established researchers who desire to learn about cancer systems biology and why it is possibly the leading front to a personalized medicine approach will enjoy reading this book.
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Keywords
- acute myeloid leukemia
- Bioinformatics
- biomarker
- Boolean model
- brain-tumor-initiating cell (BTIC)
- Breast
- Cancer
- cancer genomics
- cancer progression
- cancer stem cells
- cancer systems biology
- circulating miR-1246
- clinical trials
- CNV
- computational methods
- diagnostic biomarker
- differential expression
- docking
- drug repurposing
- drug resistance
- Elk-1
- ETS
- Ets-1
- experimental model systems
- Genomics
- Glioma
- glycomics
- glycosaminoglycan binding
- knockdown
- lung adenocarcinoma
- lung adenocarcinoma (LUAD)
- lung cancer
- lung squamous cell carcinoma (LUSC)
- medicine
- metabolomics
- Metagenomics
- microarray
- n/a
- network
- next-generation sequencing
- non-small-cell lung cancer
- omics
- optical genome mapping
- ovarian
- Pancreatic Cancer
- patient survival
- patient-derived organoids
- patient-derived xenografts
- PEA3
- personalized medicine
- PI3K–Akt signaling pathways
- prognosis
- prognostic biomarker
- protein interactome
- Proteomics
- renal cancers
- risk group
- Sestrin2
- signature
- single-cell sequencing
- SNV
- solid tumors
- stem cell
- Survival
- Systems Biology
- TargetScan
- TCGA
- Transcriptomics
- triple-negative breast cancer
- UBE2C
- virtual screening
Links
DOI: 10.3390/books978-3-0365-1471-0Editions