Explore
The book “Multiple Sclerosis: Diagnosis and Treatment” provides a collection of selected articles published in Biomedicines as part of Volume II addressing current issues on this major inflammatory demyelinating neurological disorder. The articles describe recent advances and discoveries in the molecular and cell microenvironment contributing to neuro-inflammation in the brain and spinal cord. The role of the neurofilaments light chain as a serological biomarker of axonal and neuronal degeneration of the CNS is presented not just as a sensitive diagnostic tool, but also as an indicator of treatment responses. The new generation of therapeutic molecules belonging to the sphingosine-1-phosphate class are discussed, and their potential as disease-modifying treatment is considered. Investigations into the intimate molecular mechanisms of highly active MS, disclosed clinically and by MRI, are discussed by researchers proposing that the expression of RNAs in peripheral blood cells is a biomarker of highly active disease. The book also addresses important clinical and epidemiological aspects of pediatric MS and that in multi-ethnic cohorts.
This book is included in DOAB.
Why read this book? Have your say.
You must be logged in to comment.
Rights Information
Are you the author or publisher of this work? If so, you can claim it as yours by registering as an Unglue.it rights holder.Downloads
This work has been downloaded 28 times via unglue.it ebook links.
- 28 - pdf (CC BY) at Unglue.it.
Keywords
- Acetylcholine
- acute disseminated encephalomyelitis
- biomarkers
- child neurology
- cholinergic system
- circular RNAs
- Cytokines
- demyelinating disease
- Disparities
- EAE
- glial fibrillary acidic protein
- immunomodulatory therapies
- Inflammation
- medicine
- MicroRNAs
- minority populations
- Mitochondria
- MS
- Multiple Sclerosis
- myelin oligodendrocyte glycoprotein
- myelitis
- neurofilament light chain
- neurofilaments light chain
- neuroimmunology
- neuromyelitis optica
- oligoclonal bands
- OMA1
- OPA1
- PBMCS
- pediatric multiple sclerosis
- Pediatric neurology
- PHB2
- ROS
- serum neurofilament
- sphingosine-1-phosphate modulators
- Spinal cord
- therapy-response marker
- transcriptome
Links
DOI: 10.3390/books978-3-0365-2917-2Editions