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Intervertebral Disc Regeneration
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This book provides a brief snapshot of recent research on the subject of intervertebral disc degeneration and how this specific organ could be regenerated. It provides stimuli to the reader in representing research from different angles in this cross-disciplinary field of spine surgeons, mechanical engineers and biologists. In particular, it is instructive as to how disc herniations could be successfully induced in vitro and, also, to how novel cell-based therapies using rare autochthonous stem cells could potentially be used in the future.
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Keywords
- (lumbar) disc herniation
- annulus fibrosus repair
- Biomaterials
- Biomechanics
- cell
- cell therapy
- chondrogenesis
- cryopreservation
- CryoStor 10
- Degeneration
- differentiation
- differentiation factor
- disc degeneration
- disc repair
- dynamic testing
- EZSPHERE
- GDF5
- GDF6
- growth factor
- Growth factors
- History of engineering & technology
- hyaluronic acid
- in vitro
- Inflammation
- inflammatory biomarkers and signalling pathways
- intervertebral disc
- intervertebral disc (IVD)
- losartanon
- lumbar disc herniation
- mesenchymal stromal cell
- microenvironment
- nasal chondrocytes
- nucleus pulposus
- nucleus pulposus progenitor cells
- nucleus pulposus progenitor cells (NPPC)
- physiological activities
- progenitor cells
- Regeneration
- regenerative approaches
- renin–angiotensin system
- scaffolds
- spheroid colony
- Spine
- stem cell
- Technology, engineering, agriculture
- Technology: general issues
- test method
- TGFβ
- Tie2
- Tissue Engineering
- Wnt