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Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy 2.0
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Monoclonal antibodies (mAbs) are among the most specialised molecules for the recognition and capture of specific analytes. Hundreds of thousands of mAbs have been generated for a large number of different antigens with increasing affinity and specificity and are available for the most diverse purposes. Many of them have been validated as irreplaceable agents for diagnosis and therapy or as unique reagents for research. Others have been developed using emerging technologies that avoid the need for animal immunisation. This short book strives to gather the perspective view of the various contributing authors and to survey the new strategic assets adopted to generate novel monoclonal antibodies or surrogates, such as Fab, Fab2, ScFv and nanobodies, which have an increasing impact in biomedicine as therapeutic or diagnostic assets in various diseases.
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Keywords
- antibody
- Atherosclerosis
- bio-layer interferometry
- Biology, Life Sciences
- C. auris
- candidiasis
- Cell Wall
- cell-based panning
- competitive ELISA
- epitope identification
- excipient
- FGFR3-specific antibody
- foot-and-mouth disease virus
- free radical
- human antibody
- mAb
- Magnetic Resonance Imaging
- Mathematics & science
- monoclonal antibodies
- Monoclonal antibody
- multidrug resistance
- nano-emulsion
- oxidation
- passive immunization
- phage display
- PRAME
- protein aggregation
- Reference, information & interdisciplinary subjects
- Research & information: general
- semi-automated cell panning
- stealth
- type A
- type O
- universal antibodies
Links
DOI: 10.3390/books978-3-0365-3164-9Editions