Explore
Structure, Activity, and Function of Protein Methyltransferases
0 Ungluers have
Faved this Work
Login to Fave
This collection of review articles describes the structure, function and mechanism of individual protein methyltransferase enzymes including protein lysine methyltransferases, protein arginine methyltransferases, and also the less abundant protein histidine methyltransferases and protein N-terminal end methyltransferases. The topics covered in the individual reviews include structural aspects (domain architecture, homologs and paralogs, and structure), biochemical properties (mechanism, sequence specificity, product specificity, regulation, and histone and non-histone substrates), cellular features (subcellular localization, expression patterns, cellular roles and function, biological effects of substrate protein methylation, connection to cell signaling pathways, and connection to chromatin regulation) and their role in diseases. This review book is a useful resource for scientists working on protein methylation and protein methyltransferases and those interested in joining this emerging research field.
This book is included in DOAB.
Why read this book? Have your say.
You must be logged in to comment.
Rights Information
Are you the author or publisher of this work? If so, you can claim it as yours by registering as an Unglue.it rights holder.Downloads
This work has been downloaded 77 times via unglue.it ebook links.
- 77 - pdf (CC BY) at Unglue.it.
Keywords
- Actin
- actin cytoskeleton
- AML
- arginine methylation
- Biochemistry
- Biology, Life Sciences
- Cancer
- Cardiovascular Disease
- cell proliferation
- Cell signaling
- chromatin regulation
- Congenital Heart Diseases
- Cytoskeleton
- dendritic spine
- diabetes
- Disease
- DNA damage repair
- Dystonia
- eEF1A
- EHMT1
- EHMT2
- enteroviruses
- enzyme regulation
- enzyme specificity
- epigenetics
- G9a
- GLP
- GTPase
- H3K36
- H3K36me2
- H3K4me3
- H3K9 methylation
- H3R2me2a
- H4R3 methylation
- heterochromatin
- histone
- Hsmar1
- Huntington’s disease
- Immunity
- Inflammation
- inflammatory bowel disease
- lysine methylation
- lysine-specific methyltransferase (PKMT)
- Mathematics & science
- methyltransferase
- Metnase
- METTL13
- MLL2
- N-terminal methylation
- n/a
- Neurodegenerative Diseases
- Neuron
- NHEJ
- non-homologous end joining repair
- NSD1
- NSD3
- NUP98-NSD1
- Oncogenesis
- PKMT
- Pluripotency
- Polymerization
- post translational modification
- Post-translational modification
- post-translational protein modification
- posttranslational modifications
- Prader–Willi syndrome
- PRMT1
- PRMT2
- PRMT5
- PRMT6
- PRMT7
- protein arginine methylation
- protein histidine methylation
- protein lysine methylation
- protein post-translational modification
- Reference, information & interdisciplinary subjects
- Research & information: general
- Rett Syndrome
- Schizophrenia
- SET7/9
- SETD3
- SETD7
- SETDB1
- SETMAR
- SH3
- SOTOS
- stress response
- Structure
- structure and function
- synapse
- transcriptional regulation
- Translation
- transposable elements
- transposase
- WHSC1L1
Links
DOI: 10.3390/books978-3-0365-4140-2Editions