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Hallmarks of Parkinson’s Disease
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This book gathers a collection of review articles aiming to provide an update of the current knowledge on PD pathogenesis. It notably includes an overview of several key cellular dysfunctions underlying the etiology of Parkinson’s disease, including ER stress, mitophagy and alpha-synuclein-linked pathology.
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Keywords
- alpha-syn
- alpha-Synuclein
- Astrocytes
- Biology, Life Sciences
- cell-to-cell transfer
- exocytosis
- Genetics
- Life sciences: general issues
- Lipids
- Mathematics & science
- medicine
- membranes
- Microglia
- mito-Keima
- mito-QC
- mito-SRAI
- Mitochondrial dysfunction
- mitochondrial quality control
- mitophagy
- neurodegeneration
- Neurons
- Neurosciences
- Parkin
- Parkinson Disease
- parkinson’s disease
- PINK1
- prion-like spreading
- protein quality control
- reticulum endoplasmic
- SNARE complex
- synapse
- Therapeutic target
- Ubiquitin
- Unfolded Protein Response
- vesicle fusion
- α-synuclein