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Marine Drug Research in China: Selected Papers from the 15-NASMD Conference
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The Book covers this whole field, from the discovery of structurally new and bioactive natural products (including biomacromolecules), from marine macro-/micro-organisms, to the pharmacodynamics, pharmacokinetics, metabolisms, and mechanisms of marine-derived lead compounds, both in vitro and in vivo, along with the synthesis and/or structural optimization of marine-derived lead compounds and their structure–activity relationships. Taken together, this Special Issue reprint not only provides inspiration for the discovery of marine-derived novel bioactive compounds, but also sheds light on the further research and development of marine candidate drugs.
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Keywords
- absolute configuration
- AChE inhibitory
- actinomycete
- actinomycin D
- actinomycin X2
- adenosine monophosphate-activated protein kinase (AMPK)
- ADME
- ADMET
- adsorption kinetics and isotherms
- angiotensin-I-converting enzyme (ACE) peptide
- Antarctic krill (Euphausia superba)
- anti-glioma activity
- anti-inflammatory activity
- antiaging
- antibacterial
- Antibacterial activity
- antibacterial properties
- anticancer
- antihyperlipidemic
- antimicrobial activity
- antimicrobial peptides
- antioxidant activity
- antitumor activity
- antitumor peptide
- Apoptosis
- Arca inflata
- aromatic acids
- ascidian-derived fungus
- Aspergillus flavipes HN4-13
- Aspergillus hiratsukae
- Aspergillus puniceus
- Aspergillus sclerotiorum
- Aspergillus sp.
- Aspergillus terreus
- Aspergillus unguis
- biological activities
- butenolides
- butyrolactone I
- Caenorhabditis elegans
- calmodulin
- CDK4/6
- chejuenlide
- Chronic Kidney Disease
- clavipitacae
- cognitive dysfunction
- colorectal cancer
- coral-derived fungi
- cyclic pentapeptide
- cytotoxic activity
- Cytotoxicity
- deep-sea actinomycetes
- deep-sea fungus
- deep-sea-derived fungus
- depsides
- depsidones
- Diaporthe sp.
- Drug Design
- dyeing
- emodin
- enantiomers
- endothelin-1 (ET-1)
- enrichment
- eremophilane sesquiterpenoids
- flavonoid
- fluorescent properties
- Food allergy
- fucoidan
- fucoxanthin
- galaxamide analogues
- genome mining
- geodin
- GSK3β-Nrf2-HO-1 signaling
- Hahella
- heterocornols
- IL-17 pathway
- insecticidal activity
- isoquinoline alkaloid
- LC-MS/MS
- Lecanicillium fusisporum
- lipodepsipeptide
- macroporous resin XAD-16
- mangrove endophytic Pestalotiopsis
- mangrove-derived fungus
- MAPK signaling
- marine compounds
- marine fungi
- Mechanism
- medicine
- meroterpenoids
- Metabolism
- methicillin-resistant Staphylococcus aureus
- microbial pigments
- microbiota
- Microglial Polarization
- mm-pbsa
- molecular docking
- Molecular Dynamics
- mutants
- NAFLD
- nasopharyngeal carcinoma
- neuroinflammation
- nitric oxide (NO)
- Nrf2
- nuclear factor erythroid-2-related factor 2-mediated (Nrf2)
- Oceanapia
- osteoclast differentiation
- Oxidative Stress
- oxidized low-density lipoprotein
- oximes
- oyster
- pancreatic lipase
- PD-L1
- Penicillium sp.
- peptide
- peptidome
- Pestalotiopsis heterocornis
- pharmacokinetics
- pharmacophore construction
- pharmacophore modeling
- phycocyanin
- piericidins
- Plasma
- prodiginine
- protein tyrosine phosphatase inhibitor
- pyranodipyran derivatives
- sclerotides
- Sdy-1
- secondary metabolites
- semisynthesize
- sesquiterpene glycoside
- signaling pathway
- silk
- skipjack tuna (Katsuwonus pelamis) muscle
- soft-coral-derived fungus
- Sonneratia apetala
- sponge
- sponge-derived fungus
- Stability
- Streptomyces parvulus
- tetramic acid derivatives
- Toll-like receptor 4-mediated (TLR4)
- transcriptome
- Trichoderma longibrachiatum
- tyrosyl DNA phosphodiesterase 1 inhibitory activities
- vascular endothelial cell
- virtual screening
- Wnt signaling
- Xanthones
- β-catenin