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Gluten-Related Disorders: Time to Move from Gut to Brain
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The extraintestinal manifestations of coeliac disease (CD) are now well recognised. We have previously edited a special issue for Nutrients covering all aspects of the extraintestinal manifestations in the context of CD. In this issue we wish to concentrate just on the neurological manifestations. The identification of TG6 autoantibodies in patients with neurological manifestations and its use in the diagnosis of such patients seems to be a good opportunity to focus on the neurological aspect of CD. In addition it is now clear that such manifestations can occur even in the absence of enteropathy but in the presence of antigliadin antibodies and/or TG6 antibodies. Given that such antigliadin antibodies can be found in up to 10% of the “healthy” population we anticipate that the neurological manifestations are likely to be very common and thus merit early recognition and treatment.
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Keywords
- anti-GAD antibodies
- anti-gliadin antibodies
- Anxiety
- ataxia
- Attention deficit hyperactivity disorder
- Autism Spectrum Disorder
- Autistic Spectrum Disorder
- autoimmune thyroid disease
- Autoimmunity
- Biology, Life Sciences
- Bipolar Disorder
- celiac disease
- cerebellar ataxia
- coeliac disease
- Cognition
- cortical excitability
- Cultural Studies
- Depression
- dermatitis herpetiformis
- disease duration
- duodenal lymphocytosis
- Eating Disorders
- encephalopathy
- executive dysfunction
- Food & society
- food intolerance
- gamma-amino-butyric acid
- gliadin
- gluten
- Gluten ataxia
- gluten encephalopathy
- gluten free diet
- gluten neuropathy
- gluten sensitivity
- Gluten-free diet
- gluten-related pathology
- headaches
- HLA
- Irritable Bowel Syndrome
- Mathematics & science
- MR imaging
- multiple food hypersensitivity
- Multiple Sclerosis
- Myopathy
- neurological disorders
- neurological dysfunction
- Neurology
- neuropathy
- neuropsychiatric symptoms
- non-celiac wheat sensitivity
- psoriasis
- psychiatric manifestations
- Reference, information & interdisciplinary subjects
- Research & information: general
- review
- Schizophrenia
- Society & culture: general
- Society & Social Sciences
- stiff person syndrome
- TG2
- TG3
- TG6
- TG6 antibodies
- transcallosal inhibition
- Transcranial Magnetic Stimulation
- transglutaminase antibodies
- Type 1 Diabetes
Links
DOI: 10.3390/books978-3-0365-5060-2Editions