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Photodynamic therapy (PDT) is a light-based photochemistry process. The illumination of a photoactivatable molecule (also called photosensitizer) with visible or near infrared light produces reactive oxygen toxic species to destroy tumor cells. This treatment modality leads to highly targeted actions, because reactive oxygen species are produced only where light is applied. Light is not harmful, nor is the photoactivable molecule. Only the combination of three elements (photosensitizer, oxygen, and light) is required to induce photo-oxidation reactions. PDT has proven to be a promising modality in many medical applications including cutaneous condition, infectious diseases, and various cancers at different stages. This book is a reprint of the Special Issue "Photodynamic Therapy 2021" that was published in Pharmaceuticals.
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Keywords
- 5-ALA
- 5-aminolevulinic acid
- Absorption
- actinic keratosis
- AGuIX®
- antimicrobial agents
- Bacteria
- Ceramics
- chemotherapy
- chitosan
- Clinical & internal medicine
- clinical trials
- cross-linking agents
- curcumin
- dALA
- Decontamination
- dental implant
- Diseases & disorders
- fluorescence
- fluorescent dyes
- gadolinium
- Glioblastoma
- glioblastoma multiforme
- hairless mice
- illumination time
- immune checkpoint inhibition
- Immunotherapy
- incubation time
- laser
- liposomes
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- Melanoma
- methyl aminolevulinate
- methylene blue
- murine models
- natural photosensitizer
- normal keratinocytes
- oncology
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- PDT
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- peri-implantitis
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- Photochemistry
- photodynamic therapy
- Photofrin®
- photoinactivation
- photosensitizing agents
- photothermal therapy
- PpIX
- programmed death-ligand 1 protein (PD-L1)
- prophylactic treatment
- Protein Conformation
- protoporphyrin IX
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- radiation therapy
- Resistance
- riboflavin
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- singlet oxygen
- skin cancer treatment
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- SSTI
- talaporfin sodium
- terbium
- tin complex
- U251
- Ultraviolet radiation
- X-ray-induced photodynamic therapy
- zinc (II) phthalocyanine
- β-mannose-conjugated chlorin e6
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Links
DOI: 10.3390/books978-3-0365-5351-1Editions