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Photodynamic therapy (PDT) is a light-based photochemistry process. The illumination of a photoactivatable molecule (also called photosensitizer) with visible or near infrared light produces reactive oxygen toxic species to destroy tumor cells. This treatment modality leads to highly targeted actions, because reactive oxygen species are produced only where light is applied. Light is not harmful, nor is the photoactivable molecule. Only the combination of three elements (photosensitizer, oxygen, and light) is required to induce photo-oxidation reactions. PDT has proven to be a promising modality in many medical applications including cutaneous condition, infectious diseases, and various cancers at different stages. This book is a reprint of the Special Issue "Photodynamic Therapy 2021" that was published in Pharmaceuticals.
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Keywords
- 5-ALA
- 5-aminolevulinic acid
- Absorption
- actinic keratosis
- AGuIX®
- antimicrobial agents
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- chemotherapy
- chitosan
- Clinical & internal medicine
- clinical trials
- cross-linking agents
- curcumin
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- Diseases & disorders
- fluorescence
- fluorescent dyes
- gadolinium
- Glioblastoma
- glioblastoma multiforme
- hairless mice
- illumination time
- immune checkpoint inhibition
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- laser
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- methyl aminolevulinate
- methylene blue
- murine models
- natural photosensitizer
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- Photochemistry
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- Photofrin®
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- PpIX
- programmed death-ligand 1 protein (PD-L1)
- prophylactic treatment
- Protein Conformation
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- skin cancer treatment
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- SSTI
- talaporfin sodium
- terbium
- tin complex
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- Ultraviolet radiation
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- zinc (II) phthalocyanine
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Links
DOI: 10.3390/books978-3-0365-5351-1Editions