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Targeting the Microbiome for Disease Diagnosis and Therapy
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Background: The gut microbiota is emerging as a pivotal player in the pathogenesis of many non-communicable diseases. Thus, it has been proposed as a new diagnostic and therapeutic target.Aim and scope: This Special Issue will focus on the microbiome as a potential target of new personalized therapies or diagnostic tools.History: In recent decades, the gut microbiome has been deeply investigated, and many studies have provided new information on the role of dysbiosis in many gastrointestinal and extra-gastrointestinal diseases. Recently, in addition to its phylogenetic characterization, new information has become available regarding the function of the gut microbiota, thanks to proteomic and metabolomic analyses.Cutting-edge research: The therapeutic modulation of the gut microbiota based on different strategies, including diet modification, antibiotics, prebiotics, probiotics, and, last but not least, fecal microbiota transplantation, has been tested for the treatment of various diseases. Recently, the possible applications and modalities of gut microbiota modulation have been increasingly expanding.We have collected original clinical or pre-clinical research papers and reviews focusing on the use of the microbiome for disease diagnosis, monitoring, or therapy and suggesting new possible gut microbiota-based approaches for personalized care.
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Keywords
- 16S rDNA gene diversity
- 16S RNA sequencing
- aGvHD
- analytical reproducibility
- Antibiotic-resistant bacteria
- antitumour treatment
- Anxiety
- artificial intelligence
- Autoimmunity
- beta-blocker
- biomarkers
- blood biochemical characteristics
- Cardiovascular Diseases
- Children
- Critically ill
- cystic fibrosis
- data disease subtypes
- Depression
- dip test
- driver mutation
- dysbiosis
- endometrial cancer
- endometrial microbiome
- estrobolome
- estrogen metabolism
- fecal matter transplantation
- fecal microbiota transplantation
- feces microbiome
- food components
- functional genes
- gallstone disease
- genera
- Graves–Basedow’s diseases
- gut microbiome
- Gut Microbiota
- Hashimoto’s thyroiditis
- hematopoietic stem cell transplantation
- hemodialysis
- IgA nephropathy
- Inflammation
- intermittent hypoxemia
- intestinal dysbiosis
- intestinal permeability
- Irritable Bowel Syndrome
- Machine learning
- maltodextrin
- medicine
- mesothelioma
- microbiome
- microbiota
- n/a
- next-generation sequencing
- Nutrients
- obstructive sleep apnea
- oral microbiota
- personalized medicine
- Prebiotics
- Probiotics
- probiotics and acute diverticulitis
- probiotics and diverticular disease
- probiotics and gut disease
- probiotics mechanism of action
- propensity score matching methods
- Rabbits
- random sampling
- recurrent cystitis
- Rheumatoid arthritis
- rheumatology diseases
- rifaximin
- Schizophrenia
- Sjögren’s syndrome
- Species
- systemic lupus erythematosus
- thymoma
- tonsil
- violin plots
- weight status
- α1KI-CD89Tg mice
Links
DOI: 10.3390/books978-3-0365-5611-6Editions