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Frontiers of Targeted Therapy and Predictors of Treatment Response in Systemic Sclerosis

Frontiers of Targeted Therapy and Predictors of Treatment Response in Systemic Sclerosis

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Systemic sclerosis (scleroderma) is an incurable connective tissue disease with an unclear etiology characterized by vasculopathy, dysregulation of the immune response, and progressive tissue fibrosis affecting the skin, lungs, digestive tract, heart, and kidneys. The collection of six original research manuscripts and five review articles included in this book highlights the most recent advances in this field and provides further elucidation of the pathogenesis, natural disease course, and treatment of this challenging disease.

This book is included in DOAB.

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Keywords

  • anti-inflammatory
  • Aptamers
  • Autoantibodies
  • autoimmune connective tissue diseases
  • autoreactive B cells
  • Biology, Life Sciences
  • biomarkers
  • bisphosphonates
  • body mass index
  • calcinosis cutis
  • Clinical Trial
  • complement
  • cough
  • dermatomyositis
  • epigenetic mechanisms
  • established dermal fibrosis
  • Fibrosis
  • gut dysbiosis
  • heat shock protein 90
  • idiopathic inflammatory myopathy
  • immune cells
  • interleukin-6
  • interstitial lung disease
  • ion mobility
  • kynurenine pathway
  • LC-MS/MS
  • Lipids
  • lung function
  • macitentan
  • Mathematics & science
  • metabolomics
  • miRNA
  • miRNAs
  • mixed connective tissue disease
  • Myofibroblasts
  • n/a
  • national delphi consensus
  • pamidronate
  • Pathogenesis
  • predictors of treatment response
  • progressive fibrosing interstitial lung disease
  • pulmonary arterial hypertension (PAH)
  • pulmonary fibrosis
  • pulmonary hypertension
  • Reference, information & interdisciplinary subjects
  • Research & information: general
  • Rheumatoid arthritis
  • rituximab
  • Seldeg
  • Sjögren’s syndrome
  • systemic lupus erythematosus
  • systemic sclerosis
  • Therapy
  • tocilizumab
  • Treatment
  • urea cycle

Links

DOI: 10.3390/books978-3-0365-6122-6

Editions

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