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Amyloid-β
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This reprint includes 16 original articles published in a Special Issue that focuses on the pathological significance of amyloid-β in neurodegenerative diseases, such as Alzheimer’s disease, the main cause of dementia. Collections in this reprint provide novel insights into the underlying mechanisms and therapeutic potentials of repositioning drugs and new agents for Alzheimer’s disease and related dementias. These findings are expected to contribute to the development of innovative strategies for the prevention and treatment of such diseases.
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Keywords
- activation phenotypes
- Alzheimer’s disease
- amyloid
- amyloid aggregation
- amyloid beta
- amyloid imaging
- amyloid PET
- Amyloid precursor protein
- amyloid β
- amyloid β-peptides
- amyloid β-protein (Aβ)
- amyloid-β
- amyloid-β protein
- antimicrobial
- antimicrobial peptide
- antiviral
- APP mutation
- Axon
- Aβ
- Aβ oligomers
- Bacterial amyloid
- bryostatin-1
- Cd
- Cerebellum
- cerebral amyloid angiopathy
- cerebral micro-hemorrhage(s)
- CsgA
- curli
- diosgenin
- Dutch-type mutation
- E22Q
- ECE1
- FAD
- familial Alzheimer’s disease
- Fluorescence microscopy
- FRET
- FUBA
- high-speed atomic force microscopy
- immunohistochemistry
- iPS
- Islet amyloid polypeptide
- kihito
- mAb158
- medicine
- Medicine: General Issues
- microbiota
- Microglia
- misfolding
- molecular dynamics simulation
- Molecular imaging
- Mutation
- n/a
- naringenin
- nELAV
- neurodegenerative disease
- neuroinflammation
- Neurotoxicity
- NMR
- oligomer
- oligomers
- Oxidative Stress
- PBB3
- phosphodiesterase III inhibitor
- PIB
- Polygalae Radix
- polyphenol
- pro-oxidant
- Protein Kinase C
- protofibrils
- Public health & preventive medicine
- recessive inheritance
- supplement
- supported lipid bilayers
- tau PET
- temporal cortex
- time-lapse AFM
- traditional medicines
- transgenic mice
- α-secretase
- α/β-discordant
- β-amyloid peptide