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Clinical, Pathological, and Molecular Characteristics in Colorectal Cancer
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Despite major medical advances in recent decades, colorectal cancer remains a major public health problem with significant unmet medical needs. This reprint presents new scientific and clinical data, and discusses the need to identify new theranostic biomarkers from tissue and fluid biopsies, to go further in terms of personalised medicine and thus overcome current limitations.
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Keywords
- ablation
- ACKR3
- adjuvant
- chemokine
- chemotherapy
- circulating tumor cells
- CMS
- colon cancer
- colonic neoplasms
- colorectal cancer
- discoidin domain receptor
- dual expression
- early recurrence
- Economics, finance, business & management
- epigenetics
- ERBB2
- event free survival
- extracellular vesicles
- Genome-Wide Association Study
- HER-2
- heterogeneity
- high-definition single-cell assay
- Liquid Biopsy
- liver metastases
- lung metastases
- Lynch syndrome
- Mendelian Randomization
- metastasis
- microenvironment
- mismatch repair proteins
- multi-assay
- n/a
- oncosomes
- PD-L1
- polygenic risk scores
- poor prognosis
- pre-metastatic niche
- precision medicine
- prognosis
- protein biomarker
- rare cell
- RAS mutations
- resection
- Resistance
- signaling pathways
- Snail transcription factor
- Surgery
- Survival
- Therapy
- tumor budding