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Microbial Biocatalysis
Zhilong Wang (editor) and Tao Pan (editor)
2023
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Biocatalysis is a sustainable alternative for the chemical industry in manufacturing, monitoring, and waste management. Biocatalytic processes perform with isolated enzymes or whole cells as biocatalysts. Whole-cell biocatalysts offer some unique advantages of cascade reactions catalyzed by multienzymes as well as a single bioredox reaction with cofactor regeneration in a single strain. Therefore, whole-cell biocatalysts are widely applied for biosynthesis/biotransformation to produce value-added chemicals as well as the complete mineralization of organic pollutants.Biological catalytic processing using whole-cell biocatalysts includes biocatalyst engineering, bio-reaction engineering, and downstream processing. In addition to the traditional screening of microbial strains and immobilized whole-cell biocatalysts, modern genetic engineering, metabolic engineering, and synthetic biology make tailored whole-cell biocatalysts possible. At the same time, some integrated processes have successfully been applied in the catalytic processing using living whole-cell biocatalysts, such as harnessing biocompatible chemistry to interface with the microbial metabolism as well as using various separation techniques for in situ product removal.This reprint on “Microbial Biocatalysis” provides a comprehensive overview of the recent developments of catalyst discovery, catalyst modification, and process intensification for whole cell catalysis in fermentation, biotransformation or biodegradation processes.
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Keywords
- (R)-1-phenylethanol
- Absidia coerulea
- acetophenone tolerance
- aerobic composting
- Arthrobacter sp. ST11
- atrazine
- Biochemical engineering
- Biodegradation
- biopolymers
- Biotechnology
- biotransformation
- C058
- C7-hydroxylation
- Cadmium
- cell immobilization
- culture conditions optimization
- Cunninghamella blakesleeana 3.970
- depolymerization
- DHEA
- diclofenac
- directed evolution
- Enzymes
- Extracellular Polymeric Substances
- Gibberella sp.
- glycerol
- immobilization
- laccase
- Marine enzymes
- metabolites
- microbial transformation
- microcosmic structure
- microflora composition
- multifunctional enzymes
- mycelium biofloc
- n/a
- nicotinic acid
- nitrilase
- nonaqueous-phase liquid
- nysfungin
- nystatin A1
- nystatin A3
- O-demethylation rabeprazole sulfide
- p-coumaric acid
- Persian Gulf
- phase inversion
- phenol
- phenylalanine ammonia-lyase
- phytosterols
- Pickering emulsion
- plant oil
- polyfungin B
- post-modifying enzymes
- rabeprazole
- rapeseed oil
- reaction optimization
- secondary metabolic
- semi-continuous packed-bed bioreactor
- Sewage treatment
- short-chain dehydrogenase/reductase
- starch hydrolysis
- Streptomyces noursei
- sulfide
- sustainability
- synthases
- Technology, engineering, agriculture
- Technology: general issues
- Toxicity
- trans-cinnamic acid
- UV mutagenesis
- whole genome sequencing
- whole-cell biotransformation
- whole-cell catalyst
- xenobiotics
- Yarrowia lipolytica
- α-amylase
- α-ketoglutaric acid biosynthesis
Links
DOI: 10.3390/books978-3-0365-7190-4Editions