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PARPs, PAR and NAD Metabolism and Their Inhibitors in Cancer
Nicola Curtin (editor) and Péter Bay (editor)
2023
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This Special Issue of Cancers contains research and review articles on “PARPs, PAR and NAD metabolism and their inhibitors in Cancer”. It focuses on selected papers from the PARP2019 conference on “New Avenues in Basic and Translational PARP research”, that took place in Budapest (Hungary), on 20–23 May 2019.
This book is included in DOAB.
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Keywords
- ADP-ribosyl hydrolase
- ADP-ribosylation
- AML
- Apoptosis
- apoptosis resistance
- arginine-specific mono-ADP-ribosylation
- ARH1
- ART1
- ARTD
- ARTDs
- ataxia telangiectasia and Rad3 related inhibitors (ATRi)
- ATM
- ATR
- Autophagy
- bacterial toxin
- beta-lapachone
- Biochemistry
- biogenesis
- Biology, Life Sciences
- biomarkers
- brahma-related gene 1 (BRG1)
- CAL27
- Cancer
- cancer cell
- cancer therapeutic strategy
- cancer therapeutics
- carcinogenesis
- carryover effect
- Cell Cycle
- cell cycle checkpoints
- chemotherapy
- CHK1
- cholera toxin
- cisplatin
- clinical trials
- cMet
- combination therapy
- CTLA-4
- cytoprotection
- Cytotoxicity
- distorted mitotic spindles
- DNA Damage
- DNA damage response
- DNA Repair
- Drug development
- EGFR
- ES cells
- exclusive eradication of human cancer cells
- gender bias
- gene transcription
- head and neck squamous cell carcinoma
- hematopoietic differentiation
- histone acetyltransferase p300 (EP300)
- Homologous Recombination
- homologous recombination DNA repair
- hypoxia
- immune checkpoint inhibitor
- Immunomodulation
- Immunotherapy
- irinotecan
- loss of heterozygosity
- lung cancer
- MACROD1
- MACROD2
- macrodomain
- Mathematics & science
- MDS
- membrane repair
- Metabolism
- Mitochondria
- mitochondrial protection
- mTOR
- n/a
- NAD+
- NAMPT
- NMNAT1
- NQO1
- nucleolus
- olaparib
- Osteosarcoma
- Oxidative Stress
- p60/p150 CAF-1 subunits
- Pancreatic Cancer
- PARG
- PARP
- PARP inhibitor
- PARP inhibitors
- PARP-Akt interplay
- PARP1
- PARPs
- PARylation
- PD-1
- PD-L1
- personalized treatment
- PI3K
- poly (ADP-ribose) glycohydrolase
- poly (ADP-ribose) polymerase
- poly (ADP-ribose) polymerase inhibitors (PARPi)
- poly(ADP-ribosyl)ation
- poly-ADP-ribose polymerase 1 (PARP1)
- prostate cancer
- radiosensitization
- Reference, information & interdisciplinary subjects
- replication stress
- Research & information: general
- SCC90
- solid tumors
- squamous cell carcinoma
- Syk
- synthetic lethality
- TARG1
- TDP1
- the PARP inhibitor PJ34
- TOP1 activity
- transcription
- transcription silencing
- Trapping
- Tumor microenvironment
- tumorigenesis
- UVB
Links
DOI: 10.3390/books978-3-0365-8157-6Editions