Explore
Design, Production and Characterization of Peptide Antibodies
0 Ungluers have
Faved this Work
Login to Fave
Antibodies are key reagents in diagnostics and experimental biology, capable of detecting numerous antigenic targets. Proteins are often in focus and are usually effective targets for antibody production. Occasionally, however, the native protein is known but not available, or a very specific target is required. In these cases, synthetic peptides, copying essential sequences from the target, are good alternatives for antibody production. Peptide antibodies have been used in diagnostics and experimental biology with great success, especially because they can be produced to multiple targets, for example, native and denatured targets. Traditional peptide antibody proteins encompass animal-based immunization with a synthetic peptide, usually conjugated to a carrier protein to enhance immune presentation, as small peptides tend not to be immunogenic by themselves. There are several strategies for the conjugation of peptides to carriers applied for immunization. This is the most used approach for peptide antibody production. In addition to traditional peptide antibody production, peptide antibodies can be produced using libraries or sequencing. This Special Issue, “Design, Production and Characterization of Peptide Antibodies”, aims to describe the current state-of-the-art techniques and characterization/applications within the field as well as new and emerging uses of peptide antibodies.
This book is included in DOAB.
Why read this book? Have your say.
You must be logged in to comment.
Rights Information
Are you the author or publisher of this work? If so, you can claim it as yours by registering as an Unglue.it rights holder.Downloads
This work has been downloaded 15 times via unglue.it ebook links.
- 15 - pdf (CC BY) at Unglue.it.
Keywords
- 2xVH
- anti-citrullinated protein antibodies
- antibody
- antibody production
- Arenaviridae family
- bidirectional
- Biochemistry
- Biology, Life Sciences
- bivalent bispecific molecule
- calreticulin
- citrullinated peptides
- computational modeling
- concomittant binding
- Crystal structure
- developability
- dynamic light scattering
- enzyme-linked immunosorbent assay
- epitope
- Epitopes
- heavy-chain antibody
- heavy-chain dimer
- IgG-like bispecifics
- in silico prediction
- Lassa virus
- MagPlex
- Mathematics & science
- monoclonal antibodies
- n/a
- promoters
- Protein
- Reference, information & interdisciplinary subjects
- Research & information: general
- Rheumatoid arthritis
- self-association
- self-interaction
- single-domain antibody
- soluble VH
- symmetrical bispecific
- upstream processing
- viscosity
Links
DOI: 10.3390/books978-3-0365-7691-6Editions