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Molecular Mechanisms of Synaptic Plasticity: Dynamic Changes in Neurons Functions
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The human brain has hundreds of billions of neurons, and at least 7 million dendrites have been hypothesized to exist for each neuron, with over 100 trillion neuron–neuron, neuron–muscle, and neuron–endocrine cell synapses [1,2]. Our body continually receives stimuli from the outer environment, and our brain’s ability to respond to these stimuli is ensured through synaptic processes, motivating the foundations of this Special Issue.This reprint aims to underline the role of synaptic plasticity phenomena in our body and clarify the mechanism operated by neurons to guarantee these phenomena. The collection in the Issue comprises 14 papers, including 8 reviews and 6 original works, one of which is a protocol for differentiating neurons from human stem cells, and 5 are preclinical works.
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Keywords
- Alzheimer’s disease (AD)
- AM251
- Amygdala
- Autophagy
- Biology, Life Sciences
- Brain connectivity
- Brain Development
- Brain Disorders
- brain networks
- caspase-3
- Circular Hole Board
- Cognition
- Computational neuroscience
- connectivity
- D2 receptors
- dendritic spines
- Dopamine
- dopamine transporter
- dopamine volume transmission
- dorsal striatum
- Dystonia
- endocannabinoid system
- ErbB receptors
- GABA
- glia
- Glucocorticoids
- Glutamate
- gut-brain axis
- high contrast
- Hippocampus
- human neurons
- immunoproteasome
- induced neural stem cells
- Inflammation
- Inhibition
- learning and memory
- long-term depression
- long-term potentiation
- long-term potentiation (LTP)
- LTD
- LTP
- Mathematics & science
- Mice
- midbrain dopamine neurons
- mTOR
- Multiple Sclerosis
- n/a
- neuregulins
- neuro-inflammation
- neurodevelopmental diseases
- neuronal cytoarchitecture
- neuroplasticity
- neurovascular unit
- NMDA receptors
- noradrenaline
- parkinson’s disease
- PINK1
- proteasome
- Reference, information & interdisciplinary subjects
- regulatory T cells
- Research & information: general
- resting state functional MRI (rs-fMRI)
- Reticular Formation
- Schaffer collateral-CA1 synapses
- Schizophrenia
- serotonin (5-HT)
- SNARE proteins
- spatial learning
- Striatum
- synapse
- Synapses
- synaptic plasticity
- synaptic scaling
- synaptic vesicles
- Systems Biology
- T-cells
- transmission electron microscopy
- tripartite synapse
- tyrosine hydroxylase