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Brain Injury and Neurodegeneration: Molecular, Functional, and Translational Approach
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With the advancements in the medical and scientific fields, the global community has acquired a comprehensive understanding about brain insults and pathologies. In addition, new findings and discoveries are being made globally every day, which keep our curiosity high and drive a knowledge gain. Any brain insult or pathology is multifactorial, including a cascade of inflammation, necrotic, and apoptotic pathways; can be influenced by genetic or environmental factors; and may lead to chronic neurodegeneration or disabilities. This Special Issue, entitled “Brain Injury and Neurodegeneration: Molecular, Functional, and Translational Approach”, has addressed various important aspects of brain injury and neurodegeneration, such as TBI, cerebral hypoxia, epilepsy, AD, and SARS-CoV-2-mediated brain damage. It received appreciable global response, and published 18 peer-reviewed articles, including 10 research articles and 8 reviews. Briefly, it explores the recent coronavirus infection-mediated cerebral damage; discusses the mechanism of TBI, ischemia, hypoxia, and epilepsy; talks about neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease and CONDCA; and, finally, reviews the translational values of phytochemicals in brain pathologies. In conclusion, this Special Issue provides a unique review on brain injury and neurodegeneration, and will be a good tool in enhancing knowledge in terms of brain disease-related pathology, mechanisms, and translational approach.
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Keywords
- 18F-FDG PET
- AGTPBP1
- Alzheimer’s disease
- amyloid beta
- anosmia
- anti-convulsants
- anti-epileptic drugs
- Apoptosis
- blunt-force TBI
- Brain Injury
- CCP1
- chronic alcoholism
- Clinical & internal medicine
- cognitive impairment
- CONDCA
- COVID-19
- drug targets
- edema
- epigenetics
- Epileptogenesis
- excitotoxicity
- exomiRNA
- exosome
- Extracellular matrix
- FABP3
- FABP5
- FABP7
- gene regulation
- GSK-3β
- HHV-6
- histone deacetylase
- histone deacetylase inhibitor
- hypoxia
- hypoxic-ischemic injuries
- icariin
- icaritin
- Inflammation
- ischemia
- ischemic stroke
- isomiR
- mechanical stimulations
- medicine
- Microglia
- microRNA
- middle cerebral artery occlusion
- mild traumatic brain injury
- miRNA
- Mitochondria
- moderate traumatic brain injury
- mPGES-1
- n/a
- Natural Products
- neural ischemia
- neural mitochondrial functions
- neural tissue hypoxic injuries
- neuraxis
- neuro-recovery
- neurodegeneration
- Neurodegenerative Diseases
- neuroinflammation
- Neurology & clinical neurophysiology
- Neurons
- Neuroprotection
- Neurorehabilitation
- neurotrauma
- NNA1
- non-communicable disease
- Olfactory dysfunction
- organelle dysfunction
- Oxidative Stress
- p-Tau
- parkinson’s disease
- PCD
- PGE2
- Phytochemicals
- post-traumatic seizures
- pseudo-resistance
- purmorphamine
- Reactive Oxygen Species
- RNAseq
- SARS-CoV-2
- seizures
- sonic hedgehog signaling
- Stretching
- Substantia Nigra
- TBI
- therapeutic strategies
- transcriptional modifications
- Traumatic Brain Injury
- traumatic brain injury (TBI)
- treadmill exercise
- tRNA
- Zebrafish
Links
DOI: 10.3390/books978-3-0365-8385-3Editions