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Cavitation-Enhanced Drug Delivery and Immunotherapy
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Cavitation-Enhanced Drug Delivery and Immunotherapy is a rapidly evolving area that has been buoyed in recent years by the development of methods harnessing the activity of ultrasound-stimulated bubbles, known as cavitation. When properly controlled, cavitation can help overcome physical barriers to drug delivery whilst providing readily measurable information for timely quantitative feedback and treatment guidance. Microbubble-assisted therapies have demonstrated impressive advancements in clinical trials and pre-clinical areas, including applications in neurology, oncology, cardiology and beyond.
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Keywords
- acoustic droplet vaporization
- Biochemical engineering
- Biofilm
- Biotechnology
- Cancer
- cationic microbubble
- cavitation
- cavitation nuclei
- cetuximab
- checkpoint inhibitor
- contrast-enhanced ultrasound
- Drug delivery
- endothelial cells
- focused ultrasound
- gemcitabine
- Gene Therapy
- GL261 mouse model
- Glioblastoma
- Head and Neck Cancer
- HUVEC
- immune checkpoint inhibitors
- Immunotherapy
- inertial cavitation
- Inner ear
- intravascular ultrasound
- large animal cancer model
- lonidamine
- metabolomics
- metformin
- microbubble
- microbubble targeting
- microbubbles
- microfluidic emulsion manufacturing
- microRNA-126
- miRNA delivery
- n/a
- nanoparticle
- oxygen-loaded microbubbles
- paclitaxel
- Pancreatic Cancer
- passive acoustic mapping
- passive cavitation detection
- perfluoropentane microdroplets
- perilymph
- polydispersity
- Radiotherapy
- round window membrane
- size-isolated microbubbles
- SonoCloud
- sonoporation
- SonoTran Particles
- stable cavitation
- Targeted Drug Delivery
- targeted microbubbles
- Technology, engineering, agriculture
- Technology: general issues
- therapeutic angiogenesis
- Therapy
- tumor hypoxia
- ultrasound
- ultrasound contrast agent
- ultrasound drug delivery
- ultrasound duty cycle
- ultrasound imaging probes
- ultrasound targeting
- ultrasound-mediated drug delivery
- ultrasound-targeted delivery
Links
DOI: 10.3390/books978-3-0365-9435-4Editions