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Current State of the Field of Cell-Penetrating Peptides as an Honorific Issue for Professor Ülo Langel
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This Special Issue entitled, initiated by the editorial team of Pharmaceutics, pays homage to Professor Ülo Langel for his remarkable scientific contribution to the field of cell-penetrating peptides (CPPs). Prof. Langel graduated from Tartu University, Tartu, Estonia, as a bioorganic chemist in 1974. He has obtained two PhD degrees: in 1980 from Tartu University, Tartu, Estonia (bioorganic chemistry), and in 1993 from Tartu University/Stockholm University (biochemistry/neurochemistry). Prof. Langel is a Professor at the Department of Biochemistry and Biophysics, Stockholm University, and at the Institute of Technology, Tartu University. Furthermore, he is an Associate Professor at The Scripps Research Institute, La Jolla, CA, USA and Honorary Professor at Ljubljana University, Slovenia.He has been an invited lecturer at numerous international conferences, and is a co-author of more than 450 scientific articles and 20 approved or pending patents. His main interest lies in neurochemistry, where his research is aimed at studying peptides, particularly neuropeptide receptors, and drug delivery via cell-penetrating peptides.
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Keywords
- alpha-beta peptide
- alpha-helix stabilization
- antimicrobial peptide
- antiviral peptide
- aromatic modification
- bioportide
- blood–brain barrier
- cell delivery
- cell penetrating peptide
- cell-penetrating peptide
- Cell-Penetrating Peptides
- CFTR stabilizer
- CFTR-CAL interaction
- confocal microscopy
- cystic fibrosis
- Drug delivery
- Drug Design
- Endocytosis
- eyes absent protein
- glycan recognition
- hepatitis B virus Tachyplesin (Tpl)
- hepatocellular carcinoma
- immunoglobulin
- interfering peptides
- internalization mechanism
- intracellular trafficking
- intracellular uptake
- lactoferrin
- lipid–peptide interaction
- lysosomal degradation
- machine learning techniques
- membrane binding
- mitochondria targeting
- mitochondrial DNA diseases
- mitochondrial gene therapy
- nanodelivery systems
- nanoparticle formation
- neoblast
- NickFect
- nucleic acid delivery
- oligoarginines
- p.Phe508del mutant
- PEI-based complexes
- penetrating peptides
- PepFect
- peptide delivery
- peptide engineering
- planarian
- prediction server
- protein aggregation
- secondary structure
- secretion signal peptide
- solvent
- stem cell
- stereoisomers
- transepithelial permeation
- transfection
- transportan
- tumor-penetrating peptides
- virion secretion