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ADP-Ribosylation in Pathogens
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ADP-ribosylation was discovered over 60 years ago, and much of the research focused on bacterial toxins that employed ADP-ribosylation to kill host cells. However, in the last 20 years, the field has identified many cases where host-mediated ADP-ribosylation can either promote or repress pathogenic infections. It is clear that ADP-ribosylation is a key component of the innate immune response in eukaryotes and bacteria, and many of the mechanistic details of how ADP-ribosylation impacts pathogens have yet to be uncovered. In this Special Issue, we have focused on publishing unique reviews and primary research on the topics of pathogens and ADP-ribosylation. We hope that you will enjoy this collection.
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Keywords
- 14-3-3 activated bacterial exotoxins
- Actin
- ADP-ribosylation
- ADP-ribosylhydrolase
- Aedes aegypti
- Aeromonas salmonicid
- alcoholic liver disease
- alphavirus
- alphaviruses
- antimicrobial resistance
- antiviral response
- arboviruses
- Cardiovascular Disease
- cell growth
- chikungunya virus (CHIKV)
- chronic infection
- Coronavirus
- Coronaviruses
- COVID-19
- DarT/DarG
- Diphtheria toxin-like ADP-ribosyltransferases
- DNA modification
- DNA virus
- drug discovery and development
- effector
- Emphysema
- epigenetic
- host-pathogen interaction
- Host–pathogen interactions
- host–virus evolution
- hydrolase
- IFN-I
- Immunity
- Inhibitors
- innate immunity
- interferon
- Legionella pneumophila
- leishmania
- Mac1
- macrodomain
- MARylation
- Mass Spectrometry
- non-structural protein 3 (NSP3)
- PARG
- PARP
- PARP1
- PARylation
- phage defence
- phylogenetics
- poly ADP-ribosylation
- poly(ADP-ribose) glycohydrolase
- post-translational modifications
- PR-ubiquitination
- protein refolding
- Proteomics
- Pseudomonas aeruginosa
- RNA-virus
- SARS-CoV-2
- SidE family
- tankyrase
- thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKF Pathology::MKFM Medical microbiology and virology
- thema EDItEUR::P Mathematics and Science
- thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
- thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
- Therapeutics
- toxin–antitoxin
- Trypanosoma
- type III secretion system
- viral gene regulation
- viral infection
- virtual screening
Links
DOI: 10.3390/books978-3-7258-0985-1Editions