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Ion Channels and Neurological Disease
Carlo Musio (editor)
2024
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This Special Issue reprint aims to provide an update on the state of the art and new achievements in the research on altered structure/function relationship in the ion channels involved in neurological diseases’ pathophysiology. Of particular interest are drug screening and targeting, proposing novel therapeutic avenues which can be developed to treat or alleviate mostly incurable diseases. Multi- and inter-disciplinary research contributions, often combining structural, functional, and/or pharmacological approaches with different methods/techniques, are presented.
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Keywords
- Alzheimer’s disease
- AMPA
- Amyotrophic lateral sclerosis
- Astrocytes
- Autophagy
- brain oscillations
- calcineurin
- calcium signaling
- cerebellar ataxia
- chloride transport
- CLC proteins
- Developmental
- Disease
- dorsolateral funiculus afferents
- endosome
- Epilepsy
- excitability
- excitation
- FHM3
- GABAB receptors
- glia
- Glioblastoma
- Glutamate
- Hippocampus
- induced pluripotent stem cells
- Inhibition
- Intellectual Disability
- intrinsic membrane excitability
- Ion Channels
- lysosome
- membrane excitability
- motoneurons
- n/a
- Nav channel blockers
- neurodegeneration
- neurodegenerative disease
- neuronal activity
- nucleoporins
- parkinson’s disease
- patch-clamp
- Pharmacology
- Plasticity
- Purkinje neuron
- ryanodine receptor
- Spinal cord
- thema EDItEUR::P Mathematics and Science
- thema EDItEUR::P Mathematics and Science::PH Physics::PHV Applied physics::PHVN Biophysics
- thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
- Therapy
- transporter
- voltage-gated sodium channels