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Therapeutic Drug Monitoring and Pharmacokinetics-Based Individualization of Drug Therapy
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This compilation is a reprint of the Special Issue “Therapeutic drug monitoring and pharmacokinetics-based individualization of drug therapy” of the peer-reviewed journal Pharmaceutics (ISSN: 1999-4923). The primary aim of this Special Issue was to provide a platform for presenting the findings of research performed using novel computer software-based approaches for the pharmacokinetic interpretation of the results of therapeutic drug monitoring. The compilation involves nineteen research articles and five review papers published between 2022 and 2024. The areas covered include pharmacotherapy following organ transplant, the treatment of the severely or even critically ill using antiinfectives, precision oncology, mental illness, cystic fibrosis, anticoagulant therapy, the treatment of diabetes, and ophthalmology.
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Keywords
- acute lymphoid leukemia
- acute rejection
- antibiotics
- area under the curve
- Atrial Fibrillation
- AUC
- bayesian
- Bayesian estimation
- Bayesian Models
- bioequivalence
- Biological Therapy
- biomarkers
- bipolar and related disorders
- busulfan
- cabotegravir
- caftor
- cefiderocol
- cerebrospinal fluid
- CFTR modulators
- Children
- clinical practice
- cobicistat
- covariates
- critical ill
- Critical Illness
- cystic fibrosis
- dalbavancin
- dapagliflozin
- Delirium
- Depressive Disorder
- direct oral anticoagulants
- dose–effect relationship
- dosing nomogram
- dried blood spots
- drug monitoring
- elexacaftor
- endomyocardial biopsies
- external evaluation
- external validation
- fixed-dose combination products
- fungal infection
- ganciclovir
- gentamicin
- GFR
- glomerular filtration rate
- gram-positive
- haloperidol
- heart transplant
- heart transplantation
- ICU
- imatinib
- intensive care
- isavuconazole
- ivacaftor
- kidney injury
- kinase inhibitors
- laparoscopic sleeve gastrectomy
- LC–MS/MS
- limited sampling strategies
- limited-sampling strategy
- linagliptin
- long-acting
- long-acting antiretroviral therapy
- lumacaftor
- lung transplant recipients
- medication adherence
- methotrexate
- model re-estimation
- model-informed precision dosing
- modeling and simulation
- myelofibrosis
- n/a
- non-infectious uveitis (NIU)
- nonparametric adaptive grid
- Obesity
- omeprazole
- oncology
- oral anticancer drugs
- osteoarticular infections
- outcomes
- pediatric
- pediatric pharmacology
- Pharmacodynamics
- Pharmacogenetics
- pharmacokinetic boosting
- pharmacokinetic enhancement
- pharmacokinetic interactions
- pharmacokinetic simulation
- pharmacokinetics
- piperacillin
- PK/PD
- plasma level
- population pharmacokinetic
- population pharmacokinetic modeling
- population pharmacokinetic modelling
- population pharmacokinetics
- precision medicine
- precision pharmacotherapy
- rifampicin
- rilpivirine
- ritonavir
- rivaroxaban
- robustness
- schizophrenia spectrum and other psychotic disorders
- semi-parametric simulation
- Sepsis
- small molecule kinase inhibitors
- sulfolane
- tacrolimus
- tazobactam
- TDM
- tezacaftor
- Thai patient
- thema EDItEUR::M Medicine and Nursing
- thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology
- therapeutic drug monitoring
- therapeutic drug monitoring (TDM)
- tobramycin
- treatment efficacy
- Tuberculosis
Links
DOI: 10.3390/books978-3-7258-2022-1Editions