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Microfluidics for Cells and Other Organisms
Danny van Noort
2019
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Microfluidics-based devices play an important role in creating realistic microenvironments in which cell cultures can thrive. They can, for example, be used to monitor drug toxicity and perform medical diagnostics, and be in a static-, perfusion- or droplet-based device. They can also be used to study cell-cell, cell-matrix or cell-surface interactions. Cells can be either single cells, 3D cell cultures or co-cultures. Other organisms could include bacteria, zebra fish embryo, C. elegans, to name a few.
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Keywords
- 3D flow focusing
- 3D particle focusing
- 3D printing
- absolute quantification
- adherent cells
- bacterial concentration
- Biomedical engineering
- bioMEMS
- cancer metastasis
- Cancer stem cell
- capacitively coupled contactless conductivity detection (C4D)
- capillary
- capture efficiency
- cbNIPD
- cell growth
- cell homogenous dispersion structure
- cell motility
- cells-in-gels-in-paper
- co-culture
- DNA
- drug resistance
- E. coli
- Embryogenesis
- fnRBC
- Instrumentation
- intracellular proteins
- laminar flows
- microfabrication
- microfluidic device
- microfluidic flow cytometry
- Microfluidics
- micropipette aspiration
- Microscopy
- n/a
- nanostructure
- neural networks
- nucleic acid
- on-chip cell incubator
- paracrine signaling
- particle/cell imaging
- periodic hydrostatic pressure
- periodic pressure
- pneumatic microvalve
- printed-circuit-board (PCB)
- RNA
- sample preparation
- screening
- simultaneous multiple chamber observation
- single-cell analysis
- single-cell manipulation
- single-cell mechanics
- target cell-specific binding molecules
- time-lapse observation
- unsupervised learning
- variational inference
- Wheatstone bridge
- zebrafish embryo