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Nutrition and Eye Health
John Lawrenson and Laura Downie
2020
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Blindness and visual impairment impact significantly on an individual’s physical and mental well-being. Loss of vision is a global health problem, with approximately 250 million of the world’s population currently living with vision loss, of which 36 million are classified as blind. Visual impairment is more frequent in the elderly, with cataract and age-related macular degeneration (AMD) accounting for over 50% of cases globally. Oxidative stress has been strongly implicated in the pathogenesis of both conditions, and consequently the role of nutritional factors, in particular carotenoids and micronutrient antioxidants, have been investigated as possible preventative or therapeutic strategies. Dry eye syndrome (DES) is one of the most common ophthalmic conditions in the world. DES occurs where the eye does not produce enough tears and/or the tears evaporate too quicklyleading to discomfort and varying degrees of visual disturbance. There has recently been a great deal of interest in the potential for oral or topical supplementation with essential fatty acids (EFAs), specifically omega-3 and omega-6 fatty acids, as an adjunct to conventional treatments for DES. The objective of this Special Issue on ‘Nutrition and Eye Health’ is to publish papers describing the role of nutrition in maintaining eye health and the use of nutritional interventions to prevent or treat ocular disease. A particular (but not exclusive) emphasis will be on papers (reviews and/or clinical or experimental studies) relating to cataract, AMD and DES.
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Keywords
- advanced glycation end products
- age-related macular degeneration
- AGREE II
- AMD
- Angiogenesis
- anti-inflammatory
- anti-oxidant
- antioxidant supplements
- carotenoids
- cataract
- chyrsin
- clinical practice guidelines
- clinical survey
- CODS
- corneal chemical burn
- corneal neovascularization (CNV)
- crocetin
- crocin
- Crocus Sativus L.
- Cucurbita argyrosperma
- cyclooxigenase-2 (COX-2)
- diabetes
- diabetic retinopathy
- Diet
- dietary antioxidants
- dietary assessment
- dietary habits
- Drug Discovery
- dry eye
- electroretinography
- Endoplasmic Reticulum
- Endoplasmic Reticulum Stress
- estrogen-deficient rats
- eye disease
- fatty acid
- Fish Oil
- Flavonoids
- food frequency questionnaire
- Glaucoma
- Gut Microbiota
- gut-retina axis
- Inflammation
- interleukin-1? (IL-1?)
- Lactobacillus paracasei KW3110
- LENS
- lenses
- Light
- light damage
- lutein
- macrophage
- mesozeaxanthin (RS zeaxanthin)
- Micronutrients
- microvascular lesions
- n/a
- neoangiogenesis
- nuclear factor-kappaB (NF-?B)
- Nutrition
- nutritional supplements
- Omega-3
- omega-3 polyunsaturated fatty acids
- Oxidative Stress
- personalised medicine
- photoreceptor degeneration
- phytoconstituents
- Polyphenols
- preclinical models
- reduced glutathione
- Retina
- retinal pigment epithelium
- Rosmarinic acid
- RR-zeaxanthin
- saffron
- saponins
- sinapic acid
- supplements
- Systematic Reviews
- vascular endothelial growth factor (VEGF)
- visual cycle
Links
DOI: 10.3390/books978-3-03921-991-9Editions
